Li Xiangyun, Wu Xiujie, Xu Yuanhong, Liu Yajing
Department of Laboratory Medicine, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, People's Republic of China.
Department of Laboratory Medicine, Anhui Medical University, Hefei, Anhui, People's Republic of China.
Infect Drug Resist. 2021 Dec 17;14:5411-5415. doi: 10.2147/IDR.S344062. eCollection 2021.
Bacteremia caused by is an extremely rare infection that accounts for 0.5-2% of all positive blood cultures. is an opportunistic agent that is highly lethal in immunocompromised or epithelial barrier disruption hosts.
A 74-year-old woman was admitted to our hospital with a high fever. The patient was diagnosed with an abdominal infection after a bowel invasion and recurrence of an ovarian tumor after surgery. Blood sample culturing yielded transparent, smooth, moist, slightly raised colonies without a hemolytic ring. was identified by gram staining and MALDI-TOF MS. 16S rRNA gene sequencing confirmed a sequence homologous to in the GenBank database. Drug susceptibility testing showed that was sensitive to cefoxitin, clindamycin, imipenem, meropenem, metronidazole, and vancomycin. After treatment, the patient's body temperature was normal and she was discharged from the hospital.
This is the first case report of bacteremia caused by in China and also the first report of identifying in clinical specimens by MALDI-TOF MS. This case study could increase the awareness of these infections in China.
由[细菌名称未给出]引起的菌血症是一种极其罕见的感染，占所有血培养阳性结果的0.5 - 2%。[细菌名称未给出]是一种机会致病菌，在免疫功能低下或上皮屏障破坏的宿主中具有高度致死性。
一名74岁女性因高热入院。患者在肠道侵袭及手术后卵巢肿瘤复发后被诊断为腹部感染。血样培养产生了透明、光滑、湿润、稍有凸起且无溶血环的菌落。通过革兰氏染色和基质辅助激光解吸电离飞行时间质谱（MALDI - TOF MS）鉴定出[细菌名称未给出]。16S rRNA基因测序证实与GenBank数据库中的[细菌名称未给出]序列同源。药敏试验表明[细菌名称未给出]对头孢西丁、克林霉素、亚胺培南、美罗培南、甲硝唑和万古霉素敏感。治疗后，患者体温恢复正常并出院。
这是中国首例由[细菌名称未给出]引起菌血症的病例报告，也是首次通过MALDI - TOF MS在临床标本中鉴定出[细菌名称未给出]的报告。本病例研究可提高中国对这些感染的认识。
