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免疫功能低下宿主的菌血症

Bacteremia in an Immunocompromised Host.

作者信息

Saito Ashley, Wu Simon, Kwoh Eric

机构信息

Department of Medicine VA West Los Angeles Medical Center.

出版信息

J Brown Hosp Med. 2024 Apr 1;3(2):115586. doi: 10.56305/001c.115586. eCollection 2024.

DOI:10.56305/001c.115586
PMID:40026795
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11864419/
Abstract

Clostridial bacteremia is an exceedingly rare clinical entity that can cause significant morbidity and mortality. Immunocompromised patients with insult to the gastrointestinal mucosa are especially prone to the development of clostridial sepsis based on limited existing literature. Here we report a case of a 65-year-old male nursing home resident with incompletely treated colorectal adenocarcinoma who was admitted for sepsis. He was found to have polymicrobial bacteremia with and . He was successfully treated with intravenous piperacillin/tazobactam followed by an oral regimen of amoxicillin/clavulanic acid.

摘要

梭菌血症是一种极其罕见的临床病症,可导致严重的发病和死亡。根据现有有限文献,免疫功能低下且胃肠道黏膜受损的患者尤其容易发生梭菌败血症。在此,我们报告一例65岁男性养老院居民,患有未得到充分治疗的结肠直肠癌,因败血症入院。发现他患有由[具体细菌1]和[具体细菌2]引起的多种微生物菌血症。他通过静脉注射哌拉西林/他唑巴坦成功治疗,随后接受阿莫西林/克拉维酸口服治疗方案。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/671d/11864419/ef1a25e67bfc/bhm_2024_3_2_115586_221305.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/671d/11864419/ef1a25e67bfc/bhm_2024_3_2_115586_221305.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/671d/11864419/ef1a25e67bfc/bhm_2024_3_2_115586_221305.jpg

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Bacteremia in an Immunocompromised Host.免疫功能低下宿主的菌血症
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本文引用的文献

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Bloodstream Infection and Colorectal Cancer Risk in Queensland Australia, 2000-2019.澳大利亚昆士兰州 2000-2019 年血流感染与结直肠癌风险。
Am J Med. 2023 Sep;136(9):896-901. doi: 10.1016/j.amjmed.2023.05.003. Epub 2023 May 23.
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Poly-microbial bacteremia in an immune-compromised patient.免疫功能低下患者的多微生物菌血症
Oxf Med Case Reports. 2023 Jan 18;2023(1):omac146. doi: 10.1093/omcr/omac146. eCollection 2023 Jan.
3
First Report of Bacteremia Caused by in China.中国首例由……引起的菌血症报告 。 你提供的原文中“by”后面似乎缺失了具体内容。
Infect Drug Resist. 2021 Dec 17;14:5411-5415. doi: 10.2147/IDR.S344062. eCollection 2021.
4
Osteomyelitis: an Unusual Pathogen which Highlights the Importance of Deep Tissue Sampling in Chronic Osteomyelitis.骨髓炎:一种不寻常的病原体,凸显了深部组织采样在慢性骨髓炎中的重要性。
J Bone Jt Infect. 2020 Mar 30;5(2):96-100. doi: 10.7150/jbji.43801. eCollection 2020.
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Clinical features of Clostridium bacteremia in cancer patients: A case series review.癌症患者梭菌血症的临床特征:病例系列回顾
J Infect Chemother. 2020 Jan;26(1):92-94. doi: 10.1016/j.jiac.2019.07.019. Epub 2019 Aug 10.
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Clin Infect Dis. 2010 Jan 15;50(2):133-64. doi: 10.1086/649554.
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Epidemiology of Clostridium species bacteremia in Calgary, Canada, 2000-2006.2000 - 2006年加拿大卡尔加里梭菌属菌血症的流行病学研究
J Infect. 2008 Sep;57(3):198-203. doi: 10.1016/j.jinf.2008.06.018. Epub 2008 Jul 30.
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Clin Infect Dis. 2001 Aug 1;33(3):349-53. doi: 10.1086/321883. Epub 2001 Jun 22.
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Pleural empyema due to Clostridium difficile and Clostridium cadaveris.
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