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Int J Tuberc Lung Dis. 2020 Jul 1;24(7):665-673. doi: 10.5588/ijtld.19.0501.
2
Computer aided detection of tuberculosis on chest radiographs: An evaluation of the CAD4TB v6 system.计算机辅助检测胸部 X 光片上的肺结核：CAD4TB v6 系统的评估。
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3
Prevalence of tuberculosis, HIV/AIDS, and hepatitis; in a prison of Balochistan: a cross-sectional survey.在俾路支省的一所监狱中进行的横断面调查：结核、艾滋病毒/艾滋病和肝炎的流行情况。
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4
Role of community-based active case finding in screening tuberculosis in Yunnan province of China.基于社区的主动病例发现在云南省结核病筛查中的作用。
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Performance of algorithms for tuberculosis active case finding in underserved high-prevalence settings in Cambodia: a cross-sectional study.在柬埔寨服务不足且高患病率环境中进行结核病主动发现的算法性能：一项横断面研究。
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Evaluation of the diagnostic accuracy of Computer-Aided Detection of tuberculosis on Chest radiography among private sector patients in Pakistan.评价计算机辅助检测结核病在巴基斯坦私营部门患者中的胸部 X 线摄影中的诊断准确性。
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Community-based active case finding for tuberculosis in rural western China: a cross-sectional study.中国西部农村基于社区的结核病主动病例发现：一项横断面研究。
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Int J Mycobacteriol. 2017 Jul-Sep;6(3):246-252. doi: 10.4103/ijmy.ijmy_91_17.
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Pre-treatment loss to follow-up among smear-positive TB patients in tertiary hospitals, Quetta, Pakistan.巴基斯坦奎达三级医院涂片阳性结核病患者治疗前失访情况
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An evaluation of automated chest radiography reading software for tuberculosis screening among public- and private-sector patients.针对公共部门和私营部门患者的结核病筛查自动胸部X光阅读软件评估。
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通过基于社区的移动X射线筛查和Xpert检测在俾路支省早期发现结核病病例。

Early TB case detection by community-based mobile X-ray screening and Xpert testing in Balochistan.

作者信息

Wali A, Safdar N, Manair R, Khan M D, Khan A, Kurd S A, Khalil L

机构信息

Department of Primary and Secondary Healthcare, Government of Balochistan, Quetta, Pakistan.

Centre for International Health, Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway.

出版信息

Public Health Action. 2021 Dec 21;11(4):174-179. doi: 10.5588/pha.21.0050.

DOI:10.5588/pha.21.0050
PMID:34956844
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8680181/
Abstract

SETTING

This survey was conducted at 35 sites of 20 cities in 15 districts with low programmatic TB case notifications in the past years in Balochistan.

OBJECTIVE

To assess the effectiveness of the systemic community-based screening and diagnosis for early detection of TB; and 2) to describe the characteristics and understand the strengths and weaknesses of the intervention in Balochistan, and sociodemographic factors associated with it.

DESIGN

This cross-sectional descriptive study was conducted using a mobile van equipped with a digital X-ray machine with computer-aided detection for TB (CAD4TB) software for screening, followed by confirmatory high sensitivity Xpert® MTB/RIF assay testing.

RESULTS

A total of 236 (3.4%) TB cases was detected out of 6,899 screened. About 1,168 (17%) presumptive TB cases were identified and 1,065 (91%) sputum samples were tested on Xpert. Among those diagnosed, 166 (70%) were -positive and 70 (30%) were with clinical suspicion. Of the sputum samples tested, 87% (923/1065) had a probability score of >70 on CAD4TB.

CONCLUSION

Community-based screening with innovative activities, comprising sensitive screening and diagnostic tools, effectively improves TB case detection, which might suffice to reduce the prevalence of TB and break the chain of infection transmission in the at-risk population.

摘要

背景

本调查在俾路支省过去几年结核病规划病例报告率较低的15个地区的20个城市的35个地点进行。

目的

1）评估基于社区的系统筛查和诊断对结核病早期发现的有效性；2）描述俾路支省干预措施的特点，了解其优势和劣势以及与之相关的社会人口学因素。

设计

本横断面描述性研究使用一辆配备数字X光机及结核病计算机辅助检测（CAD4TB）软件的移动车进行筛查，随后进行高灵敏度Xpert® MTB/RIF检测以确诊。

结果

在6899名接受筛查者中，共检测出236例（3.4%）结核病病例。共识别出约1168例（17%）疑似结核病病例，对1065份（91%）痰标本进行了Xpert检测。在确诊的病例中，166例（70%）检测结果为阳性，70例（30%）为临床疑似病例。在接受检测的痰标本中，87%（923/1065）在CAD4TB上的概率得分>70。

结论

通过包括敏感筛查和诊断工具在内的创新活动进行基于社区的筛查，可有效提高结核病病例检出率，这可能足以降低结核病患病率并打破高危人群中的感染传播链。