Lemon Joanne L, McMenamy Michael J
Sustainable Agri-Food and Sciences Division, Agri-Food and Bioscience Institute, Newforge Lane, Belfast BT9 5PX, UK.
Veterinary Sciences Division, Agri-Food and Bioscience Institute, Stormont, Belfast BT4 3SD, UK.
Vaccines (Basel). 2021 Nov 27;9(12):1403. doi: 10.3390/vaccines9121403.
Vaccination is widely regarded as a cornerstone in animal or herd health and infectious disease management. Nineteen vaccines against the major pathogens implicated in bovine respiratory disease are registered for use in the UK by the Veterinary Medicines Directorate (VMD). However, despite annual prophylactic vaccination, bovine respiratory disease is still conservatively estimated to cost the UK economy approximately £80 million per annum. This review examines the vaccine types available, discusses the surrounding literature and scientific rationale of the limitations and assesses the potential of novel vaccine technologies.
疫苗接种被广泛认为是动物或畜群健康及传染病管理的基石。英国兽药管理局（VMD）已注册了19种针对牛呼吸道疾病主要病原体的疫苗在英国使用。然而，尽管每年都进行预防性接种，但据保守估计，牛呼吸道疾病每年仍给英国经济造成约8000万英镑的损失。本综述研究了现有的疫苗类型，讨论了相关文献以及局限性背后的科学原理，并评估了新型疫苗技术的潜力。
