• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

在回肠造口关闭前进行自主肠液回输可改善短期结局。

Self-administered succus entericus reinfusion before ileostomy closure improves short-term outcomes.

机构信息

Department of Emergency Surgery, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.

Department of Gastroenterology, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.

出版信息

BMC Surg. 2021 Dec 28;21(1):440. doi: 10.1186/s12893-021-01444-4.

DOI:10.1186/s12893-021-01444-4
PMID:34961502
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8713408/
Abstract

OBJECTIVE

The study aims to assess whether reinfusion of succus entericus prior to ileostomy closure can decrease postoperative length of stay and ameliorate low anterior resection score.

METHODS

This study is a retrospective analysis based on prospectively collected data. Patients were screened from May 2016 to November 2019. A total of 30 patients who underwent reinfusion with succus entericus (SER) were enrolled in the SER group and 42 patients without SER were enrolled in the non-SER group.

RESULTS

There was no significant difference in the incidence of postoperative ileus between succus entericus reinfusion (SER) group and the control group. Time to first passage of flatus or stool after surgery in the SER group (27.9 ± 6.02 h) is significantly shorter than the control group (32.3 ± 6.26, hours p = 0.004). Compared with the control group (5.52 (4.0-7.0) days), postoperative length of stay in the SER group was 4.90 (3.0-7.0)days (p = 0.009). As for low anterior resection score(LARS), the SER group had a lower score 1 week after discharge than the control group (p = 0.034). However, 1 month after discharge, the LARS in the two groups had no significant difference.

CONCLUSIONS

Self-administered succus entericus reinfusion is a feasible prehabilitation management for outpatients and can improve better outcomes. Compared with non-reinfusion group, succus enterius reinfusion group displays significantly shorter time for gastrointestinal function recovery and postoperative hospital stay without increasing complication, and it can bring better quality of life in a short term.

摘要

目的

本研究旨在评估在回肠造口关闭前输注肠液是否可以减少术后住院时间并改善低位前切除术评分。

方法

本研究基于前瞻性收集的数据进行回顾性分析。患者筛选时间为 2016 年 5 月至 2019 年 11 月。共有 30 例接受肠液输注(SER)的患者纳入 SER 组,42 例未接受 SER 的患者纳入非 SER 组。

结果

肠液输注(SER)组和对照组术后肠麻痹的发生率无显著差异。SER 组术后首次排气或排便时间(27.9±6.02 小时)明显短于对照组(32.3±6.26 小时,p=0.004)。与对照组(5.52(4.0-7.0)天)相比,SER 组术后住院时间为 4.90(3.0-7.0)天(p=0.009)。在低位前切除术评分(LARS)方面,SER 组出院后 1 周的评分低于对照组(p=0.034)。然而,出院后 1 个月,两组的 LARS 无显著差异。

结论

自我管理的肠液输注是一种可行的门诊前康复管理方法,可以改善预后。与非输注组相比,肠液输注组胃肠道功能恢复时间和术后住院时间明显缩短,且无并发症增加,在短期内可带来更好的生活质量。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0576/8713408/244b1b30ce2e/12893_2021_1444_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0576/8713408/aa568ca9bd62/12893_2021_1444_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0576/8713408/d93d1a5ba359/12893_2021_1444_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0576/8713408/244b1b30ce2e/12893_2021_1444_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0576/8713408/aa568ca9bd62/12893_2021_1444_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0576/8713408/d93d1a5ba359/12893_2021_1444_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0576/8713408/244b1b30ce2e/12893_2021_1444_Fig3_HTML.jpg

相似文献

1
Self-administered succus entericus reinfusion before ileostomy closure improves short-term outcomes.在回肠造口关闭前进行自主肠液回输可改善短期结局。
BMC Surg. 2021 Dec 28;21(1):440. doi: 10.1186/s12893-021-01444-4.
2
Treatment of postoperative peritonitis of small-bowel origin with continuous enteral nutrition and succus entericus reinfusion.采用持续肠内营养和肠液回输治疗小肠源性术后腹膜炎。
Arch Surg. 2002 Mar;137(3):296-300. doi: 10.1001/archsurg.137.3.296.
3
[Application of small intestine double stoma and succus entericus reinfusion in the patients with severe intra-abdominal infection].小肠双造口及肠液回输在重症腹腔感染患者中的应用
Zhonghua Wei Chang Wai Ke Za Zhi. 2015 Jul;18(7):667-70.
4
Method for Establishing Continuous Reinfusion of Succus Entericus in Complex High-output Fistula.肠液持续再灌注在复杂高输出瘘管中的建立方法。
Surg Laparosc Endosc Percutan Tech. 2020 Jun;30(3):227-232. doi: 10.1097/SLE.0000000000000757.
5
Correction to: Self-administered succus entericus reinfusion before ileostomy closure improves short-term outcomes.对《回肠造口关闭术前自行输注肠液可改善短期结局》一文的更正
BMC Surg. 2023 Sep 19;23(1):283. doi: 10.1186/s12893-023-02195-0.
6
Inhibition of upper gastrointestinal secretions by reinfusion of succus entericus into the distal small bowel. A clinical study of 30 patients with peritonitis and temporary enterostomy.通过将肠液回输至远端小肠来抑制上消化道分泌。对30例腹膜炎和临时肠造口术患者的临床研究。
Ann Surg. 1983 Nov;198(5):596-600. doi: 10.1097/00000658-198311000-00006.
7
Stimulation of the efferent limb before ileostomy closure: a randomized clinical trial.回肠造口关闭术前传出支刺激:一项随机临床试验。
Dis Colon Rectum. 2014 Dec;57(12):1391-6. doi: 10.1097/DCR.0000000000000237.
8
Chyme Reinfusion Is Associated with Lower Rate of Postoperative Ileus in Crohn's Disease Patients After Stoma Closure.肠液再输注与克罗恩病患者肠造口关闭术后术后肠麻痹发生率降低相关。
Dig Dis Sci. 2020 Jan;65(1):243-249. doi: 10.1007/s10620-019-05753-w. Epub 2019 Jul 31.
9
Proteins of the succus entericus from the jejunum of the sheep.来自绵羊空肠的肠液中的蛋白质。
Biochem J. 1966 Jul;100(1):19-26. doi: 10.1042/bj1000019.
10
Study protocol evaluating the use of bowel stimulation before loop ileostomy closure to reduce postoperative ileus: a multicenter randomized controlled trial.评估术前肠道刺激在回肠袢式造口关闭术中减少术后肠梗阻的应用效果的研究方案:一项多中心随机对照试验。
Colorectal Dis. 2017 Nov;19(11):1024-1029. doi: 10.1111/codi.13720.

引用本文的文献

1
Use of parenteral nutrition in the management of enterocutaneous fistula.肠外营养在肠皮肤瘘管理中的应用。
Nutr Clin Pract. 2025 Feb;40(1):64-75. doi: 10.1002/ncp.11245. Epub 2024 Nov 27.
2
ILEOSTIM trial: a study protocol to evaluate the effectiveness of efferent loop stimulation before ileostomy reversal.ILEOSTIM 试验:评估回肠造口还纳术前刺激输出袢对疗效的影响的研究方案
Tech Coloproctol. 2023 Dec;27(12):1251-1256. doi: 10.1007/s10151-023-02807-0. Epub 2023 Apr 27.
3
Rectal stimulation with prebiotics and probiotics before ileostomy reversal: a study protocol for a randomized controlled trial.

本文引用的文献

1
Colorectal cancer.结直肠癌。
Lancet. 2019 Oct 19;394(10207):1467-1480. doi: 10.1016/S0140-6736(19)32319-0.
2
Randomized clinical trial of prophylactic transanal irrigation supportive therapy to prevent symptoms of low anterior resection syndrome after rectal resection.直肠切除术后预防性经肛门灌洗支持治疗预防低位前切除综合征症状的随机临床试验。
BJS Open. 2019 Mar 18;3(4):461-465. doi: 10.1002/bjs5.50160. eCollection 2019 Aug.
3
Chyme Reinfusion Is Associated with Lower Rate of Postoperative Ileus in Crohn's Disease Patients After Stoma Closure.
经回肠造口还纳术前应用益生元和益生菌进行直肠刺激:一项随机对照试验的研究方案。
Trials. 2023 Jan 17;24(1):31. doi: 10.1186/s13063-023-07065-x.
肠液再输注与克罗恩病患者肠造口关闭术后术后肠麻痹发生率降低相关。
Dig Dis Sci. 2020 Jan;65(1):243-249. doi: 10.1007/s10620-019-05753-w. Epub 2019 Jul 31.
4
Prediction model and web-based risk calculator for postoperative ileus after loop ileostomy closure.经回肠袢式造口术关闭术后肠麻痹的预测模型和基于网络的风险计算器。
Br J Surg. 2019 Nov;106(12):1676-1684. doi: 10.1002/bjs.11235. Epub 2019 Jul 17.
5
Normative Data for the Low Anterior Resection Syndrome Score (LARS Score).低位前切除综合征评分(LARS 评分)的常模数据。
Ann Surg. 2019 Jun;269(6):1124-1128. doi: 10.1097/SLA.0000000000002750.
6
Incidence and predictors of postoperative ileus after loop ileostomy closure: a systematic review and meta-analysis.回肠袢式造口关闭术后肠麻痹的发生率及预测因素:系统评价和荟萃分析。
Surg Endosc. 2019 Aug;33(8):2430-2443. doi: 10.1007/s00464-019-06794-y. Epub 2019 Apr 17.
7
Stringent fluid management might help to prevent postoperative ileus after loop ileostomy closure.严格的液体管理可能有助于预防袢式回肠造口关闭术后的肠梗阻。
Langenbecks Arch Surg. 2019 Feb;404(1):39-43. doi: 10.1007/s00423-018-1744-4. Epub 2019 Jan 3.
8
Loop transverse colostomy versus loop ileostomy for defunctioning of colorectal anastomosis: a systematic review, updated conventional meta-analysis, and cumulative meta-analysis.用于结直肠吻合口减功能的袢式横结肠造口术与袢式回肠造口术:一项系统评价、更新的传统荟萃分析和累积荟萃分析
Surg Today. 2019 Feb;49(2):108-117. doi: 10.1007/s00595-018-1708-x. Epub 2018 Aug 27.
9
Application of an enhanced recovery pathway for ileostomy closure: a case-control trial with surprising results.应用强化康复路径行回肠造口还纳术:一项令人惊讶的结果的病例对照试验。
Tech Coloproctol. 2018 Apr;22(4):295-300. doi: 10.1007/s10151-018-1778-1. Epub 2018 May 3.
10
Diversion colitis and pouchitis: A mini-review. diverted colitis and pouchitis: 一个小型综述。
World J Gastroenterol. 2018 Apr 28;24(16):1734-1747. doi: 10.3748/wjg.v24.i16.1734.