Lévy E, Palmer D L, Frileux P, Parc R, Huguet C, Loygue J
Ann Surg. 1983 Nov;198(5):596-600. doi: 10.1097/00000658-198311000-00006.
We prospectively studied peritonitis secondary to small bowel leakage in 30 critically ill patients, each of whom had complete diversion of intestinal continuity by stoma, fistula, or both. All patients received total parenteral nutrition during implementation of the protocol. The proximal intestinal effluent was collected and recycled into the distal small bowel. During reinfusion of succus entericus, a significant reduction in the output of the proximal stoma was observed (mean 30.2%, p less than 0.001). The reinfusion also significantly reduced the volume from isolated small bowel loops in six patients (32.6%, p less than 0.001). When isotonic dialysate solution was infused into the distal intestine, a lesser though significant reduction in stoma output occurred (mean 20.3%, p less than 0.001). These findings demonstrate a consistent inhibitory effect upon upper gastrointestinal secretions by reinfusion of succus entericus. Clinical benefits of this technique include simplified control of fluid and electrolyte balance in patients with high output stomas and optimal utilization of remaining absorptive capacity for enteral nutrition.
我们对30例危重症患者继发于小肠渗漏的腹膜炎进行了前瞻性研究,这些患者均通过造口、瘘管或两者实现了肠道连续性的完全改道。在实施该方案期间,所有患者均接受了全胃肠外营养。收集近端肠液并回输至远端小肠。在回输肠液期间,观察到近端造口的排出量显著减少(平均减少30.2%,p<0.001)。回输还显著减少了6例患者孤立小肠袢的容量(减少32.6%,p<0.001)。当向远端肠道输注等渗透析液时,造口排出量也出现了较小但显著的减少(平均减少20.3%,p<0.001)。这些发现表明,回输肠液对上消化道分泌具有持续的抑制作用。该技术的临床益处包括简化高排出量造口患者的液体和电解质平衡控制,以及优化剩余肠内营养吸收能力的利用。