Zhu Jinguo, Wang Jian, He Yuan, Zhuang Haiwen, Yang Jinyun
Department of Gastrointestinal Surgery, The Second People's Hospital of Huai'an, Jiangshu Huai'an 223300, China.
Zhonghua Wei Chang Wai Ke Za Zhi. 2015 Jul;18(7):667-70.
To evaluate the application of small intestine double stoma and succus entericus reinfusion in the patients with severe intra-abdominal infection.
Ten patients with high intestinal perforation from February 2005 to November 2014 were enrolled in the study. All the cases received emergency operation. Small bowel with intestinal perforation was resected, and double stoma was applied in the proximal and distal small intestine. When abdominal infection under control, total enteral nutrition was successfully administered from nasogastric tube. The succus entericus from the proximal intestine was collected and transfused back to the distal intestine. Stool was collected and fecal nitrogen, fat and carbohydrate contents were determined. Related serum protein levels were measured.
As compared to pre-reinfusion, the absorption rate of carbohydrate [(90.9±7.8)% vs. (82.7±15.2)%], fat [(87.6±6.4)% vs. (59.1±10.8)%], and nitrogen [(82.4±9.8)% vs. (67.2±15.4)%] increased after succus entericus reinfusion (P<0.05). The serum protein levels increased significantly as well[fibronectin: (285.6±3.6) vs. (157.0±22.6) mg/L, P<0.01; transferrin: (4.86±0.21) vs. (3.60±0.25) g/L, P<0.05; pre-albumin: (291.3±112.5) vs. (199.1±53.3) mg/L, P<0.05].
Small intestine double stoma and succus entericus reinfusion are effective in improving the absorption of carbohydrate, fat and nitrogen in the patients with severe intra-abdominal infection.
评估小肠双造口及肠液回输在严重腹腔感染患者中的应用。
选取2005年2月至2014年11月期间10例高位小肠穿孔患者纳入研究。所有病例均接受急诊手术。切除穿孔小肠，在小肠远近端行双造口。待腹腔感染控制后，经鼻胃管成功实施全肠内营养。收集近端小肠的肠液并回输至远端小肠。收集粪便并测定粪便中氮、脂肪及碳水化合物含量。检测相关血清蛋白水平。
与回输前相比，肠液回输后碳水化合物吸收率[（90.9±7.8）% 对（82.7±15.2）%]、脂肪吸收率[（87.6±6.4）% 对（59.1±10.8）%]及氮吸收率[（82.4±9.8）% 对（67.2±15.4）%]均升高（P<0.05）。血清蛋白水平也显著升高[纤维连接蛋白：（285.6±3.6）对（157.0±22.6）mg/L，P<0.01；转铁蛋白：（4.86±0.21）对（3.60±0.25）g/L，P<0.05；前白蛋白：（291.3±112.5）对（199.1±53.3）mg/L，P<0.05]。
小肠双造口及肠液回输可有效改善严重腹腔感染患者碳水化合物、脂肪及氮的吸收。
