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水解单宁和缩合单宁的饮食摄入调节脂质代谢。

Dietary Intake of Hydrolyzable Tannins and Condensed Tannins to Regulate Lipid Metabolism.

机构信息

College of Medical Science, China Three Gorges University, Yichang, China.

Third-Grade Pharmacological Laboratory on Chinese Medicine Approved by State Administration of Traditional Chinese Medicine, Medical College of China Three Gorges, Yichang, China.

出版信息

Mini Rev Med Chem. 2022;22(13):1789-1802. doi: 10.2174/1389557522666211229112223.

Abstract

Lipid metabolism disorder is a multifactor issue, which contributes to several serious health consequences, such as obesity, hyperlipidemia, atherosclerosis diabetes, non-alcoholic fatty liver, etc. Tannins, applied as naturally derived plants, are commonly used in the study of lipid metabolism disease with excellent safety and effectiveness while producing less toxic and side effects. Meanwhile, recognition of the significance of dietary tannins in lipid metabolism disease prevention has increased. As suggested by existing evidence, dietary tannins can reduce lipid accumulation, block adipocyte differentiation, enhance antioxidant capacity, increase the content of short-chain fatty acids, and lower blood lipid levels, thus alleviating lipid metabolism disorder. This study is purposed to sum up and analyze plenty of documents on tannins, so as to provide the information required to assess the lipid metabolism of tannins.

摘要

脂代谢紊乱是一个多因素问题,可导致多种严重的健康后果,如肥胖、高脂血症、动脉粥样硬化、糖尿病、非酒精性脂肪肝等。单宁作为天然来源的植物,在脂代谢疾病的研究中应用广泛,安全性和有效性好,且产生的毒性和副作用较小。同时,人们对膳食单宁在脂代谢疾病预防中的重要性的认识也在不断提高。现有证据表明,膳食单宁可以减少脂质堆积、阻止脂肪细胞分化、增强抗氧化能力、增加短链脂肪酸含量、降低血脂水平,从而缓解脂代谢紊乱。本研究旨在对大量单宁相关文献进行总结和分析,为评估单宁的脂代谢作用提供信息。

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