Dardalhon M, Averbeck D, Moré C, Berteaud A J, Ravary V
Int J Radiat Biol Relat Stud Phys Chem Med. 1987 Aug;52(2):325-35. doi: 10.1080/09553008714551781.
The possible existence of thermal effects specific to microwaves at 2.45 GHz and not found with classical heating in a waterbath was studied by measuring cell survival (colony-forming ability) and cell viability (the ability to exclude trypan blue) in Chinese hamster V79 cells. The microwaves were employed at high power densities (125 to 175 mW/cm2) corresponding to specific absorption rates ranging between 62 and 87 mW/g. When matching the rises in temperature, the effects of microwave-induced hyperthermia at 125 mW/cm2 on cell survival were comparable to those of classical heating. However, they were statistically significantly different when using power densities of 150 and 175 mW/cm2. The response obtained in terms of cell viability appeared to be comparable. The conclusions are also valid when taking into account a correction factor for energy losses during microwave treatment. The apparent specific effect of microwaves appears to be associated with exposures at high power densities involving short treatment times and rapid rises in temperature.
通过测量中国仓鼠V79细胞的细胞存活率（集落形成能力）和细胞活力（排除台盼蓝的能力），研究了2.45 GHz微波特有的热效应的可能存在情况，而在水浴中的传统加热方式下未发现这种效应。微波以高功率密度（125至175 mW/cm2）使用，对应于62至87 mW/g的比吸收率。当温度升高相匹配时，125 mW/cm2的微波诱导热疗对细胞存活的影响与传统加热相当。然而，当使用150和175 mW/cm2的功率密度时，它们在统计学上有显著差异。在细胞活力方面获得的反应似乎相当。在考虑微波治疗期间能量损失的校正因子时，这些结论也是有效的。微波的明显特定效应似乎与高功率密度下的暴露有关，这种暴露涉及短治疗时间和快速升温。
