School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
University Research Institute of Maternal and Child Health & Precision Medicine, UNESCO Chair on Adolescent Health Care, National and Kapodistrian University of Athens, Aghia Sophia Children's Hospital, Athens, Greece.
Adv Exp Med Biol. 2021;1337:77-82. doi: 10.1007/978-3-030-78771-4_9.
Obstructive sleep apnea (OSA) is a sleep disorder with high prevalence and significant health consequences. The aim of this study was to validate the STOP-Bang Questionnaire, a widely used screening tool for OSA besides polysomnography, in Greek patients. A hundred and two (102) patients with OSA, aged [mean (SD)] 59.16 (8.53) years, and 102 healthy adults, aged [mean (SD)] 54.67 (9.36) years, were assessed. Sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) were calculated for different cut-off values. The Epworth Sleepiness Scale (ESS) was also used to examine predictive validity. Patients with OSA showed higher scores than healthy controls (p < 0.001). The resulting specificity, sensitivity, PPV, and NPV were 98%, 60%, 71%, 97%, (cut-off 3), 96%, 81%, 84%, 95% (cut-off 4), and 86%, 97%, 97%, 88% (cut-off 5), respectively. This study has demonstrated that the Greek version of STOP-Bang can be used in the clinical setting to differentiate patients with OSA from healthy individuals with high accuracy and at low cost.
阻塞性睡眠呼吸暂停（OSA）是一种患病率高且对健康有重大影响的睡眠障碍。本研究旨在验证 STOP-Bang 问卷，这是一种除多导睡眠图外广泛用于 OSA 筛查的工具，在希腊患者中的有效性。102 例 OSA 患者（年龄 [均数 (标准差)] 59.16 [8.53] 岁）和 102 例健康成年人（年龄 [均数 (标准差)] 54.67 [9.36] 岁）接受了评估。计算了不同截断值的敏感性、特异性、阳性预测值（PPV）和阴性预测值（NPV）。还使用 Epworth 嗜睡量表（ESS）来检查预测有效性。OSA 患者的得分高于健康对照组（p<0.001）。结果显示，截断值为 3 时，特异性、敏感性、PPV 和 NPV 分别为 98%、60%、71%、97%，截断值为 4 时分别为 96%、81%、84%、95%，截断值为 5 时分别为 86%、97%、97%、88%。本研究表明，希腊版 STOP-Bang 可用于临床环境中，以高精度和低成本区分 OSA 患者和健康个体。
