Skin and Stem Cell Research Center, Tehran University of Medical Sciences, Tehran, Iran; Jordan Dermatology and Hair Transplantation Center, Tehran, Iran.
Skin and Stem Cell Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Tissue Cell. 2022 Feb;74:101717. doi: 10.1016/j.tice.2021.101717. Epub 2021 Dec 27.
Tissue Engineering is a branch of regenerative medical technology which helps replace damaged tissue using appropriate scaffolding, living cells, and growth factors. Using tissue engineering products can be a promising method for treating skin lesions such as wounds and deep burns. The interaction and interconnection of cells within the bio-culture medium or within a three-dimensional scaffold provides the conditions for tissue regeneration and subsequent healing of skin wounds. Tissue engineering in the field of dermatology has evolved over time from a single application of skin cells or biopolymer scaffolds to the use of cell and scaffold combinations for the treatment, repair, and closure of acute and chronic skin wounds. It has evolved. This technology has reached a point where most products are accepted, and the body rejects a small number, which strengthens the tissue engineering market. In this article, we aimed to review and study the market of this field by reviewing various articles on tissue engineering in the field of dermatology. Tissue-engineered skin substitutes are future options for wound healing and tissue regeneration strategies.
组织工程学是再生医学技术的一个分支，它使用适当的支架、活细胞和生长因子来帮助替换受损组织。使用组织工程产品可能是治疗皮肤损伤（如伤口和深度烧伤）的一种有前途的方法。生物培养介质或三维支架内的细胞相互作用和连接为组织再生和随后的皮肤伤口愈合提供了条件。皮肤科领域的组织工程学随着时间的推移已经从单一应用皮肤细胞或生物聚合物支架发展到使用细胞和支架组合来治疗、修复和闭合急性和慢性皮肤伤口。这项技术已经达到了大多数产品都被接受的程度，只有少数产品被身体排斥，这增强了组织工程学市场。在本文中，我们旨在通过回顾皮肤科领域的各种关于组织工程学的文章来审查和研究该领域的市场。组织工程化皮肤替代物是伤口愈合和组织再生策略的未来选择。
