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胰腺脂肪变性:智利人群中的常见发现。

Pancreatic steatosis: A frequent finding in a Chilean population.

机构信息

Sección de Gastroenterología, Departamento de Medicina, Hospital Clínico Universidad de Chile, Santiago, Chile.

Sección de Gastroenterología, Departamento de Medicina, Hospital Clínico Universidad de Chile, Santiago, Chile.

出版信息

Rev Gastroenterol Mex (Engl Ed). 2023 Apr-Jun;88(2):118-124. doi: 10.1016/j.rgmxen.2021.12.008. Epub 2021 Dec 31.

DOI:10.1016/j.rgmxen.2021.12.008
PMID:34974993
Abstract

INTRODUCTION AND AIMS

Pancreatic steatosis is an incidental radiologic finding in asymptomatic patients, and its clinical importance is unclear.

PRIMARY AIM

to study the prevalence of pancreatic steatosis (PS) in consecutive patients registered at our hospital, that underwent computed axial tomography (CAT) scanning of the abdomen and pelvis, excluding known pancreatic diseases. Secondary aim: to review the association of PS with the demographic and clinical data of the patients, as well as with hepatic steatosis (HS).

MATERIALS AND METHODS

An observational study was conducted on adult patients that had CAT scans of the abdomen and pelvis.

DEFINITIONS

a) tissue density was measured in Hounsfield units (HU) in five 1 cm areas of the pancreas, three areas of the spleen, and in segments VI and VII of the liver; b) fatty pancreas: a difference < -10 HU between the mean pancreas and mean spleen densities; and c) fatty liver: density < 40 HU. We registered the epidemiologic and laboratory data of the patients. The association of those factors with the presence of PS was analyzed using SPSS version 24.0 software, and statistical significance was set at a p < 0.05.

RESULTS

Of the 203 patients, PS was found in 61 (30%). The patients with PS were significantly older and had a higher body mass index. We found no significant association with the rest of the parameters studied, nor with HS (55 patients). None of the patients had symptoms attributable to a disease of the exocrine pancreas.

CONCLUSIONS

Fatty infiltration of the pancreas is a frequent finding in CAT scans, and its clinical importance is unclear. Aging of the population and the increase in obesity underline the need for future studies on PS.

摘要

介绍和目的

胰腺脂肪变性是无症状患者偶然发现的放射学表现,其临床意义尚不清楚。

主要目的

研究我院连续登记的接受腹部和骨盆计算机轴向断层扫描(CAT)检查且无已知胰腺疾病的患者中胰腺脂肪变性(PS)的患病率。次要目的:回顾 PS 与患者的人口统计学和临床数据以及与肝脂肪变性(HS)的相关性。

材料和方法

对接受腹部和骨盆 CAT 扫描的成年患者进行了一项观察性研究。

定义

a)在胰腺的五个 1cm 区域、脾脏的三个区域以及肝脏的 VI 和 VII 段测量组织密度,以亨氏单位(HU)表示;b)脂肪胰腺:胰腺平均密度与脾脏平均密度之间的差值< -10 HU;c)脂肪肝:密度< 40 HU。我们登记了患者的流行病学和实验室数据。使用 SPSS 版本 24.0 软件分析这些因素与 PS 存在的相关性,统计显著性设为 p<0.05。

结果

在 203 名患者中,发现 61 名(30%)存在 PS。患有 PS 的患者明显年龄较大,体重指数较高。我们没有发现与其余研究参数之间存在显著相关性,也没有与 HS(55 名患者)存在相关性。没有患者出现归因于胰腺外分泌疾病的症状。

结论

胰腺脂肪浸润是 CAT 扫描中的常见发现,其临床意义尚不清楚。人口老龄化和肥胖症的增加强调了未来对 PS 进行研究的必要性。

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