Seixas Rui, Campoamor David, Lopes João, Bernardo Teresa, Nzwalo Hipólito, Pascoalinho Dulce
Department of Internal Medicine, Unidade Local de Saúde do Litoral Alentejano, Santiago do Cacém, PRT.
Stroke Unit, Algarve University Hospital Center, Faro, PRT.
Cureus. 2021 Nov 17;13(11):e19655. doi: 10.7759/cureus.19655. eCollection 2021 Nov.
Viral infections are frequently present before the clinical manifestation of Guillain-Barre syndrome (GBS). Multiple studies on coronaviruses have shown that these viruses have neurotropic characteristics, and their molecular mimicry can induce inflammatory demyelinating neuropathy. Herein, we describe a case of a GBS in an 85-year-old patient infected with SARS-CoV-2, manifested with acute progressive symmetric ascending quadriparesis, urinary dysautonomia, and dysphagia, who responded well to treatment with intravenous human immunoglobulin.
在吉兰-巴雷综合征（GBS）临床表现出现之前，病毒感染常常已经存在。多项针对冠状病毒的研究表明，这些病毒具有嗜神经性特征，并且它们的分子模拟可诱发炎性脱髓鞘性神经病。在此，我们描述一例85岁感染严重急性呼吸综合征冠状病毒2（SARS-CoV-2）的患者发生GBS的病例，该患者表现为急性进行性对称性上行性四肢瘫、排尿自主神经功能障碍和吞咽困难，经静脉注射人免疫球蛋白治疗后反应良好。
