Department of Cardiology, Royal Melbourne Hospital, Melbourne, VIC, Australia.
Department of Cardiology, The Alfred Hospital, Melbourne, VIC, Australia.
Qual Life Res. 2022 Aug;31(8):2375-2385. doi: 10.1007/s11136-021-03056-0. Epub 2022 Jan 3.
During the COVID-19 pandemic, widespread public health measures were implemented to control community transmission. The association between these measures and health-related quality of life (HRQOL) among patients following percutaneous coronary intervention has not been studied.
We included consecutive patients undergoing percutaneous coronary intervention (PCI) in the state-wide Victorian Cardiac Outcomes Registry between 1/3/2020 and 30/9/2020 (COVID-19 period; n = 5024), with a historical control group from the identical period one year prior (control period; n = 5041). HRQOL assessment was performed via telephone follow-up 30 days following PCI using the 3-level EQ-5D questionnaire and Australian-specific index values.
Baseline characteristics were similar between groups, but during the COVID-19 period indication for PCI was more common for acute coronary syndromes. No patients undergoing PCI were infected with COVID-19 at the time of their procedure. EQ-5D visual analogue score (VAS), index score, and individual components were higher at 30 days following PCI during the COVID-19 period (all P < 0.01). In multivariable analysis, the COVID-19 period was independently associated with higher VAS and index scores. No differences were observed between regions or stage of restrictions in categorical analysis. Similarly, in subgroup analysis, no significant interactions were observed.
Measures of HRQOL following PCI were higher during the COVID-19 pandemic compared to the previous year. These data suggest that challenging community circumstances may not always be associated with poor patient quality of life.
在 COVID-19 大流行期间，实施了广泛的公共卫生措施来控制社区传播。这些措施与经皮冠状动脉介入治疗（PCI）后患者的健康相关生活质量（HRQOL）之间的关系尚未得到研究。
我们纳入了 2020 年 3 月 1 日至 2020 年 9 月 30 日期间（COVID-19 期间）在全州范围内维多利亚州心脏结局登记处接受 PCI 的连续患者（n=5024），并纳入了前一年同期（对照期；n=5041）相同时期的历史对照组。在 PCI 后 30 天，通过电话随访使用 3 级 EQ-5D 问卷和澳大利亚特定的指数值来评估 HRQOL。
两组患者的基线特征相似，但在 COVID-19 期间，PCI 的指征更常见于急性冠状动脉综合征。在进行 PCI 时，没有患者感染 COVID-19。在 COVID-19 期间，EQ-5D 视觉模拟评分（VAS）、指数评分和各个组成部分在 PCI 后 30 天更高（均 P<0.01）。在多变量分析中，COVID-19 期间与更高的 VAS 和指数评分独立相关。在分类分析中，未观察到地区或限制阶段之间存在差异。同样，在亚组分析中，也未观察到显著的交互作用。
与前一年相比，COVID-19 大流行期间 PCI 后 HRQOL 更高。这些数据表明，严峻的社区环境并不总是与患者生活质量差相关。
