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γ射线辐照后人红细胞膜及红细胞影的膜电导率和流动性变化

Alteration of membrane conductivity and fluidity in human erythrocyte membranes and erythrocyte ghosts following gamma-irradiation.

作者信息

Bonincontro A, Cametti C, Rosi A, Sportelli L

出版信息

Int J Radiat Biol Relat Stud Phys Chem Med. 1987 Sep;52(3):447-57. doi: 10.1080/09553008714551911.

DOI:10.1080/09553008714551911
PMID:3497897
Abstract

Alterations of electrical properties of human erythrocyte membranes induced by gamma irradiation have been studied by means of conductivity measurements in the frequency range from 10 KHz to 100 MHz. The results clearly demonstrate the role played by haemoglobin in the structural modification of the membrane produced by gamma irradiation. Further support for this point of view has been derived from electron spin resonance measurements carried out on the same samples, labelled with different spin labels which probe the outer half layer of membrane at different penetration levels.

摘要

通过在10千赫兹至100兆赫兹频率范围内进行电导率测量,研究了γ射线辐照对人红细胞膜电特性的影响。结果清楚地表明了血红蛋白在γ射线辐照引起的膜结构改变中所起的作用。对这一观点的进一步支持来自于对相同样品进行的电子自旋共振测量,这些样品用不同的自旋标记物进行标记,这些标记物在不同的穿透水平下探测膜的外半层。

相似文献

1
Alteration of membrane conductivity and fluidity in human erythrocyte membranes and erythrocyte ghosts following gamma-irradiation.γ射线辐照后人红细胞膜及红细胞影的膜电导率和流动性变化
Int J Radiat Biol Relat Stud Phys Chem Med. 1987 Sep;52(3):447-57. doi: 10.1080/09553008714551911.
2
[Application of electron spin labeling to investigate the effects of gamma-irradiation on erythrocyte membranes].[应用电子自旋标记法研究γ射线辐照对红细胞膜的影响]
Shi Yan Sheng Wu Xue Bao. 1985 Sep;18(3):293-9.
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Radiation-induced lipid peroxidation and the fluidity of erythrocyte membrane lipids.辐射诱导的脂质过氧化与红细胞膜脂质的流动性
Free Radic Biol Med. 1987;3(2):147-52. doi: 10.1016/s0891-5849(87)80010-2.
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Effect of gamma irradiation on membranes of normal and pathological erythrocytes (beta-thalassemia).γ射线辐照对正常及病理状态(β地中海贫血)红细胞膜的影响
Radiat Environ Biophys. 1987;26(1):81-4. doi: 10.1007/BF01211366.
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Effects of gamma-irradiation on the erythrocyte membrane: ESR, NMR and biochemical studies.γ射线辐照对红细胞膜的影响:电子自旋共振、核磁共振及生化研究。
Int J Radiat Biol Relat Stud Phys Chem Med. 1987 Jan;51(1):59-69. doi: 10.1080/09553008714550501.
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Ionizing radiation-induced structural modification of human red blood cells.电离辐射诱导的人类红细胞结构改变。
Radiat Environ Biophys. 1991;30(1):45-52. doi: 10.1007/BF01595573.
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Irradiation increases proteolysis in erythrocyte ghosts: a spin label study.辐射增加红细胞影中的蛋白水解作用:一项自旋标记研究。
Radiat Environ Biophys. 1992;31(2):117-21. doi: 10.1007/BF01211209.
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Structural modification of human erythrocyte membranes following gamma-irradiation.γ射线辐照后人红细胞膜的结构修饰
Int J Radiat Biol Relat Stud Phys Chem Med. 1980 Aug;38(2):147-58. doi: 10.1080/09553008014551041.
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Evidence for a change in the fluidity of erythrocyte membranes following X irradiation by measurement of pyrene excimer fluorescence.通过芘准分子荧光测量法研究X射线照射后红细胞膜流动性变化的证据。
Radiat Res. 1979 Dec;80(3):484-93.
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Effect of hyperthermia and ionizing radiation on the erythrocyte membrane.
Int J Radiat Biol Relat Stud Phys Chem Med. 1982 Jul;42(1):45-55. doi: 10.1080/09553008214550901.

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