Cantafora A, Ceccarini M, Guidoni L, Ianzini F, Minetti M, Viti V
Int J Radiat Biol Relat Stud Phys Chem Med. 1987 Jan;51(1):59-69. doi: 10.1080/09553008714550501.
The effects of gamma-irradiation on resealed erythrocyte ghosts have been examined with different techniques. Phospholipid analysis reveals peroxidative damage on the polyunsaturated chains of phosphatidylethanolamine. Gel electrophoresis and ESR measurements indicate modifications of the cytoskeletal proteins. 31P Nuclear magnetic resonance data show bilayer modifications that can be interpreted as changes in lipid-protein interactions. The overall picture from the present results favours interaction between lipids and proteins in the inner monolayer of the membrane.
已采用不同技术研究了γ射线辐照对重新封闭的红细胞血影的影响。磷脂分析显示磷脂酰乙醇胺的多不饱和链发生了过氧化损伤。凝胶电泳和电子自旋共振测量表明细胞骨架蛋白发生了改变。磷-31核磁共振数据显示双层结构发生了改变，这可解释为脂-蛋白相互作用的变化。目前结果的总体情况表明膜内单层中脂质与蛋白质之间存在相互作用。
