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2型糖尿病代谢年龄的新评分:身体评分

A New Score for Metabolic Age in Type 2 Diabetes Mellitus: Physical Rating Score.

作者信息

Yücel Hasan Esat, Ulcay Tufan, Görgülü Özkan, Öncü Ruken, Uğuz Emre, Dulkadiroğlu Erkan

机构信息

Department of Internal Medicine, Faculty of Medicine, Ahi Evran University, Kırsehir 40100, Turkey.

Department of Anatomy, Faculty of Medicine, Ahi Evran University, Kırsehir 40100, Turkey.

出版信息

J Clin Med. 2025 Apr 22;14(9):2868. doi: 10.3390/jcm14092868.

Abstract

: Metabolic age (met-age), a risk marker, may vary within the same chronological age group. Its association with chronological age, waist/height ratio, obesity degree, body mass index (BMI), and physical rating score (PRS)-risk factors for type 2 diabetes-remains unexplored. : A total of 122 type 2 diabetes patients (50 males, 72 females) were analyzed. Bioimpedance measurements were taken using the Tanita MC-780MA, alongside anthropometric data. Variables were compared, and correlations with met-age were assessed. : The met-age-chronological age difference was higher in females with type 2 diabetes ( < 0.001). Females also had higher BMI, obesity degree, fat mass, and waist/height ratio ( < 0.05), but lower waist/hip ratio ( < 0.001). Males showed higher PRS, muscle mass, and fat-free mass ( < 0.001). Met-age positively correlated with chronological age and negatively with PRS in both sexes ( < 0.05). According to the linear regression model, in females, the met-age was influenced positively by chronological age and waist/height ratio and negatively by PRS (R = 0.983). In males, it was positively influenced by chronological age, obesity grade, and BMI, but negatively by PRS (R = 0.974). : Met-age correlates with chronological age and PRS in type 2 diabetes patients. It increases with advancing age and lower PRS, with waist/height ratio impacting females and BMI/obesity degree affecting males.

摘要

代谢年龄(met-age)作为一种风险标志物,在相同的实足年龄组内可能会有所不同。其与实足年龄、腰高比、肥胖程度、体重指数(BMI)以及身体评分(PRS)(2型糖尿病的风险因素)之间的关联仍未得到探究。

共分析了122例2型糖尿病患者(50名男性,72名女性)。使用百利达MC - 780MA测量生物阻抗,并同时获取人体测量数据。对各项变量进行比较,并评估与代谢年龄的相关性。

2型糖尿病女性患者的代谢年龄与实足年龄之差更高(<0.001)。女性的BMI、肥胖程度、脂肪量和腰高比也更高(<0.05),但腰臀比更低(<0.001)。男性的PRS、肌肉量和去脂体重更高(<0.001)。代谢年龄在两性中均与实足年龄呈正相关,与PRS呈负相关(<0.05)。根据线性回归模型,在女性中,代谢年龄受实足年龄和腰高比的正向影响,受PRS的负向影响(R = 0.983)。在男性中,它受实足年龄、肥胖等级和BMI的正向影响,但受PRS的负向影响(R = 0.974)。

代谢年龄与2型糖尿病患者的实足年龄和PRS相关。它随着年龄增长和PRS降低而增加,腰高比对女性有影响,BMI/肥胖程度对男性有影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ed41/12072852/85cf28015467/jcm-14-02868-g001.jpg

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