Department of Surgical Sciences, Uppsala University, 751 35, Uppsala, Sweden.
Centre for Clinical Research, Uppsala University, Region Västmanland, Uppsala, Sweden.
Surg Endosc. 2022 Jul;36(7):5339-5347. doi: 10.1007/s00464-021-08915-y. Epub 2022 Jan 3.
In some studies, high endoscopic retrograde cholangiopancreatography (ERCP) case-volume has been shown to correlate to high success rate in terms of successful cannulation and fewer adverse events. The aim of this study was to analyze the association between ERCP success and complications, and endoscopist and centre case-volumes.
Data were obtained from the Swedish National Register for Gallstone Surgery and ERCP (GallRiks) on all ERCPs performed for Common Bile Duct Stone (CBDS) (n = 17,873) and suspected or confirmed malignancy (n = 6152) between 2009 and 2018. Successful cannulation rate, procedure time, intra- and postoperative complication rates and post-ERCP pancreatitis (PEP) rate, were compared with endoscopist and centre ERCP case-volumes during the year preceding the procedure as predictor.
In multivariable analyses of the CBDS group adjusting for age, gender and year, a high endoscopist case-volume was associated with higher successful cannulation rate, lower complication and PEP rates, and shorter procedure time (p < 0.05). Centres with a high annual case-volume were associated with high successful cannulation rate and shorter procedure time (p < 0.05), but not lower complication and PEP rates. When indication for ERCP was malignancy, a high endoscopist case-volume was associated with high successful cannulation rate and low PEP rates (p < 0.05), but not shorter procedure time or low complication rate. Centres with high case-volume were associated with high successful cannulation rate and low complication and PEP rates (p < 0.05), but not shorter procedure time.
The results suggest that higher endoscopist and centre case-volumes are associated with safer ERCP and successful outcome.
在一些研究中,高内镜逆行胰胆管造影术(ERCP)的病例数量与成功插管率和不良事件发生率较低呈正相关。本研究旨在分析 ERCP 成功率和并发症与内镜医师和中心病例数量之间的关系。
数据来自瑞典胆囊结石手术和 ERCP 国家登记处(GallRiks),涵盖了 2009 年至 2018 年间所有用于胆总管结石(CBDS)(n=17873)和疑似或确诊恶性肿瘤(n=6152)的 ERCP。比较了在术前一年的内镜医师和中心 ERCP 病例数量作为预测因素时,成功率、手术时间、围手术期并发症和 ERCP 后胰腺炎(PEP)的发生率。
在多变量分析中,调整年龄、性别和年份后,高内镜医师病例数量与更高的插管成功率、更低的并发症和 PEP 发生率以及更短的手术时间相关(p<0.05)。每年有大量病例的中心与高插管成功率和较短的手术时间相关(p<0.05),但与低并发症和 PEP 发生率无关。当 ERCP 的指征为恶性肿瘤时,高内镜医师病例数量与高插管成功率和低 PEP 发生率相关(p<0.05),但与较短的手术时间或低并发症发生率无关。高病例量的中心与高插管成功率、低并发症和 PEP 发生率相关(p<0.05),但与较短的手术时间无关。
结果表明,较高的内镜医师和中心病例数量与更安全的 ERCP 和更好的结果相关。