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超细胆管镜联合低剂量阿托品治疗Oddi括约肌间结石的初步经验

Initial experience with ultrafine choledochoscopy combined with low-dose atropine for the treatment of Oddi intersphincter stones.

作者信息

Hu Xiao-Si, Wang Yong, Pan Hong-Tao, Zhu Chao, Zhou Shuai, Chen Shi-Lei, Liu Hui-Chun, Pang Qing, Jin Hao

机构信息

Department of Hepatopancreatobiliary Surgery, Anhui No. 2 Provincial People's Hospital, Hefei 230041, Anhui Province, China.

出版信息

World J Gastrointest Surg. 2025 Mar 27;17(3):102998. doi: 10.4240/wjgs.v17.i3.102998.

Abstract

BACKGROUND

In recent years, the use of ultrafine choledochoscopy has gradually increased in the treatment of cholelithiasis. However, stone incarceration and residual spasm of the sphincter of Oddi may be inevitable when an ultrafine choledochoscope is used alone.

AIM

To investigate the safety and feasibility of ultrafine choledochoscopy combined with low-dose atropine in the treatment of Oddi intersphincter stones.

METHODS

Seventeen patients with Oddi intersphincter stones were retrospectively analyzed. The perioperative clinical data and follow-up information were collected.

RESULTS

Among the 17 patients, 3 were male and 14 were female. The mean age was 40.6 ± 13.9 years, and the mean diameter of the common bile duct was 7.8 ± 1.3 mm. All patients successfully underwent Oddi intersphincter stone removal using a combination of ultrafine choledochoscopy and low-dose atropine. No serious complications, such as postoperative hemorrhage, pancreatitis or bile leakage occurred in the 17 patients. During the one-year follow-up, none of the patients experienced stone recurrence.

CONCLUSION

Ultrafine choledochoscopy combined with low-dose atropine is safe and feasible for the treatment of Oddi intersphincter stones.

摘要

背景

近年来,超细胆道镜在胆石症治疗中的应用逐渐增多。然而,单独使用超细胆道镜时,结石嵌顿和Oddi括约肌残余痉挛可能不可避免。

目的

探讨超细胆道镜联合小剂量阿托品治疗Oddi括约肌间结石的安全性和可行性。

方法

回顾性分析17例Oddi括约肌间结石患者。收集围手术期临床资料和随访信息。

结果

17例患者中,男性3例,女性14例。平均年龄为40.6±13.9岁,胆总管平均直径为7.8±1.3mm。所有患者均成功采用超细胆道镜联合小剂量阿托品进行Oddi括约肌间结石取出术。17例患者均未发生术后出血、胰腺炎或胆漏等严重并发症。在1年的随访期间,所有患者均未出现结石复发。

结论

超细胆道镜联合小剂量阿托品治疗Oddi括约肌间结石安全可行。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4b0b/11948106/3999e7550972/102998-g001.jpg

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