Schmitt J P, Schwoerer D, Diemunsch P, Gauthier-Lafaye J
Ann Fr Anesth Reanim. 1987;6(4):267-8. doi: 10.1016/S0750-7658(87)80036-9.
So as to ascertain whether propofol passed into human milk, a study was carried out in five women who had undergone general anaesthesia with propofol in the puerperium. Concentrations of propofol were measured both in plasma and colostrum. The results showed clearly the excretion of propofol in the colostrum, and the similar time-courses of propofol levels in the blood and colostrum; the ratio of concentrations blood:colostrum was close to 1.
为确定丙泊酚是否会进入母乳，对五名在产褥期接受丙泊酚全身麻醉的女性进行了一项研究。测量了血浆和初乳中丙泊酚的浓度。结果清楚地显示了丙泊酚在初乳中的排泄情况，以及血液和初乳中丙泊酚水平相似的时间进程；血液与初乳浓度之比接近1。
