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[膝关节镜检查的麻醉:丙泊酚与硫喷妥钠和氟烷的比较]

[Anesthesia for arthroscopy of the knee: propofol versus thiopental and halothane].

作者信息

Boittiaux P, Morelle G, Krivosic-Horber R

出版信息

Ann Fr Anesth Reanim. 1987;6(4):324-6. doi: 10.1016/s0750-7658(87)80050-3.

Abstract

Sixty ASA I or II patients, who underwent general anaesthesia for arthroscopy of the knee, were separated into two groups. Induction was performed either with thiopentone 7 mg . kg-1 (group I) or with propofol 2.5 mg . kg-1 (group II). All patients were intubated and ventilated. Dextromoramide was used as analgesic. Maintenance of anaesthesia was obtained with halothane inhalation (group I) or by continuous automatic injection of propofol at a dose of 9 mg . kg-1 . h-1 (group II). Induction and maintenance were satisfactory in both groups. Pulse rate was stable at induction and intubation for the propofol group, whereas it increased at both stages of anaesthesia with thiopentone; it fell moderately in both groups afterwards. Systolic and diastolic blood pressures dropped more in the propofol group after induction, with a maximum decrease of 20%. Recovery was significantly more rapid and comfortable with propofol than with thiopentone.

摘要

60例接受膝关节镜检查全身麻醉的美国麻醉医师协会(ASA)分级为I或II级的患者被分为两组。诱导麻醉时,一组(I组)使用硫喷妥钠7 mg·kg-1,另一组(II组)使用丙泊酚2.5 mg·kg-1。所有患者均行气管插管并机械通气。右吗拉胺用作镇痛药。I组通过吸入氟烷维持麻醉,II组通过以9 mg·kg-1·h-1的剂量持续自动注射丙泊酚维持麻醉。两组的诱导和维持麻醉效果均令人满意。丙泊酚组在诱导和插管时脉搏率稳定,而硫喷妥钠组在麻醉的两个阶段脉搏率均升高;之后两组脉搏率均有适度下降。诱导后丙泊酚组收缩压和舒张压下降幅度更大,最大降幅达20%。与硫喷妥钠相比,丙泊酚使患者恢复得明显更快且更舒适。

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