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马来西亚一名表面免疫功能正常的宿主中并发免疫重建炎症综合征的脑膜炎

meningitis complicated by immune reconstitution inflammatory syndrome in an apparent immunocompetent host in Malaysia.

作者信息

Chang Chee Yik, Mohd Shah Syarul Hafiz, Lio Jia Yin, Bahari Norazlah, Radhakrishnan Anuradha P

机构信息

Infectious Disease Unit, Medical Department, Hospital Selayang, 68100, Batu Caves, Selangor, Malaysia.

Microbiology Unit, Pathology Department, Hospital Selayang, 68100, Batu Caves, Selangor, Malaysia.

出版信息

Med Mycol Case Rep. 2021 Dec 15;35:1-4. doi: 10.1016/j.mmcr.2021.12.004. eCollection 2022 Mar.

DOI:10.1016/j.mmcr.2021.12.004
PMID:34984166
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8693149/
Abstract

Cryptococcosis is a systemic fungal infection caused by or causes a wide range of diseases, ranging from asymptomatic pulmonary lesions to disseminated disease involving the central nervous system, particularly meningoencephalitis. infection has rarely been reported in Malaysia. We present a case of meningitis with pulmonary cryptococcosis complicated by immune reconstitution inflammatory syndrome in an apparently immunocompetent person with no prior travel history.

摘要

隐球菌病是一种由……引起的全身性真菌感染，可引发多种疾病，从无症状的肺部病变到累及中枢神经系统（尤其是脑膜脑炎）的播散性疾病。在马来西亚，该感染的报道很少。我们报告一例明显免疫功能正常且无既往旅行史的患者发生肺隐球菌病合并免疫重建炎症综合征的隐球菌性脑膜炎病例。 （注：原文中“caused by or ”表述不完整，可能影响准确理解。）

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/13f0/8693149/cb8e96012ee1/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/13f0/8693149/82106aabf210/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/13f0/8693149/53783511a36d/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/13f0/8693149/cb8e96012ee1/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/13f0/8693149/82106aabf210/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/13f0/8693149/53783511a36d/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/13f0/8693149/cb8e96012ee1/gr3.jpg

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J Paediatr Child Health. 2019 Aug;55(8):943-947. doi: 10.1111/jpc.14321. Epub 2018 Dec 8.
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Successful treatment of Cryptococcus neoformans immune reconstitution inflammatory syndrome in an immunocompetent host using thalidomide.
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Cureus. 2024 May 25;16(5):e61085. doi: 10.7759/cureus.61085. eCollection 2024 May.
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Disseminated Cryptococcosis Post Eculizumab Therapy: A Case Report and Literature Review.依库珠单抗治疗后播散性隐球菌病：一例报告及文献综述
Cureus. 2024 Apr 23;16(4):e58852. doi: 10.7759/cureus.58852. eCollection 2024 Apr.
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