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[婴幼儿呼吸道感染中显著升高的IgG特异性抗体滴度与临床演变形式之间的直接关系。病程中IgA和IgD水平]

[Direct relation between the significantly increased IgG specific antibody titer and the clinico-evolutive form in respiratory infections in infants and children. IgA and IgD levels in the evolution].

作者信息

Roman S, Plavoşin L, Laky M, Buzilă L

出版信息

Rev Ig Bacteriol Virusol Parazitol Epidemiol Pneumoftiziol Bacteriol Virusol Parazitol Epidemiol. 1982 Apr-Jun;27(2):81-90.

PMID:7146761
Abstract

Of 69 children suffering from acute respiratory infections, with increased IgG titers 34 presented normal or high IgAs titers in the laryngotracheal exudate. All these patients had a favourable evolution. The other children with low IgAs levels or absent IgAs in the laryngotracheal exudate had a prolonged relapsing evolution, regardless of serum IgG levels. The presence of IgA 7S in the laryngotracheal exudate did not influence the course of the disease. As a conspicuous parallelism was observed between laryngotracheal exudate IgAs and serum IgA it was assumed that IgAs participates in the formation of serum IgA "mixtures". Increased IgD values were found in 34 of these patients, ten of whom presented respiratory allergy and recurrent infections.

摘要

在69例患有急性呼吸道感染且IgG滴度升高的儿童中,34例喉气管分泌物中的IgA滴度正常或升高。所有这些患者病情进展良好。其他喉气管分泌物中IgA水平低或无IgA的儿童,无论血清IgG水平如何,病情都呈迁延复发。喉气管分泌物中7S IgA的存在并不影响疾病进程。由于观察到喉气管分泌物IgA与血清IgA之间存在明显的平行关系,因此推测IgA参与血清IgA“混合物”的形成。在这些患者中有34例IgD值升高,其中10例有呼吸道过敏和反复感染。

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