Department of Psychiatry, National Clinical Research Center on Mental Disorders, China National Technology Institute on Mental Disorders, the Second Xiangya Hospital of Central South University, Changsha, 410011, China.
School of Psychology, Centre for Studies of Psychological Applications, Guangdong Key Laboratory of Mental Health and Cognitive Science, Ministry of Education Key Laboratory of Brain Cognition and Educational Science, South China Normal University, Guangzhou, China.
BMC Psychiatry. 2022 Jan 5;22(1):13. doi: 10.1186/s12888-021-03658-5.
People living with HIV (PLWH) carry a high risk for mental health problems, which has been extensively reported in the literature. However, an understanding of mental health characteristics in different subgroups of PLWH is still limited. In the present study, we conducted a cross-sectional survey to explore mental health characteristics and their associations with childhood trauma in two major subgroups of PLWH in China.
A total of 533 PLWH (213 prisoners in the prison system, and 320 outpatients) were assessed using the 8-item Positive Subscale of the Community Assessment of Psychic Experiences (CAPE-P8), Generalized Anxiety Disorder scale (GAD-7), Patient Health Questionnaire (PHQ-9), and Childhood Trauma Questionnaire (CTQ).
From the total sample, 22.0% PLWH frequently experienced psychotic-like experiences (PLEs), 21.8% had clinically significant anxiety syndrome, 34.0% had clinically significant depressive syndrome, and 63.6% experienced at least one type of traumatic exposure during their childhood, with physical neglect being the most common. Compared to outpatients with HIV, prisoners living with HIV reported more severe mental health problems and a higher frequency of childhood trauma, with childhood trauma in turn predicting higher risk for mental health problems. Similarly, among outpatients living with HIV, both childhood emotional and sexual abuse had predictive effects on all the three mental health problems.
The study suggests that PLWH have higher risk of anxiety, depression and PLEs, and childhood trauma could serve as predicting factors for such risks. In addition, childhood trauma may play distinct roles in predicting the risk for the mental health problems, depending on different subgroup of PLWH.
HIV 感染者(PLWH)存在较高的心理健康问题风险,这在文献中已有广泛报道。然而,对于 PLWH 不同亚组的心理健康特征,人们的了解仍有限。本研究通过横断面调查,探究了中国两大 PLWH 亚组的心理健康特征及其与童年创伤的关系。
采用社区心理体验评定量表 8 项正性量表(CAPE-P8)、广泛性焦虑障碍量表(GAD-7)、患者健康问卷(PHQ-9)和童年创伤问卷(CTQ),对 533 名 PLWH(监狱系统 213 名囚犯,门诊 320 名)进行评估。
在总样本中,22.0%的 PLWH 经常出现类精神病体验(PLEs),21.8%有临床显著的焦虑综合征,34.0%有临床显著的抑郁综合征,63.6%在童年时期至少经历过一种创伤暴露,其中身体忽视最为常见。与门诊 HIV 感染者相比,监狱 HIV 感染者报告的心理健康问题更严重,童年创伤发生率更高,而童年创伤反过来又预示着更高的心理健康问题风险。同样,在门诊 HIV 感染者中,童年期情感和性虐待均对所有三种心理健康问题具有预测作用。
研究表明,PLWH 患焦虑、抑郁和 PLEs 的风险较高,童年创伤可能是这些风险的预测因素。此外,童年创伤可能在预测 PLWH 不同亚组的心理健康问题风险方面发挥不同的作用。