Guo Lianghao, Bo Wenfei, Wang Kaicheng, Wang Shaomeng, Gong Yubin
School of Electronic Science and Engineering, University of Electronic Science and Technology of China, Chengdu, Sichuan 610054, China.
National University of Defense Technology, Xi'an, Shaanxi 710106, China.
iScience. 2021 Dec 3;25(1):103561. doi: 10.1016/j.isci.2021.103561. eCollection 2022 Jan 21.
The question of whether terahertz (THz) waves can interact with ions in channels of nerve cells and cause a further reaction has attracted much attention. To answer this question, we investigate the spontaneous radiation generated by Ca moving in calcium channels and the effect of THz radiation on the transport of Ca by solving the mathematical physical model through Brownian dynamics (BD) simulations. It is obtained that the moving Ca in a calcium channel can generate electromagnetic radiation, the corresponding spectrum of which is concentrated in the THz range. Meanwhile, both the ion number in the channel and the background temperature are proved to have significant effects on the spontaneous emission spectra. The studies also show that external THz radiation can accelerate Ca transport through the ion channel. These results are expected to provide a theoretical basis for the future treatment of THz waves in the neurological field.
太赫兹（THz）波是否能与神经细胞通道中的离子相互作用并引发进一步反应的问题备受关注。为回答这个问题，我们通过布朗动力学（BD）模拟求解数学物理模型，研究了钙在钙通道中移动时产生的自发辐射以及太赫兹辐射对钙运输的影响。结果表明，钙通道中移动的钙能产生电磁辐射，其相应频谱集中在太赫兹范围内。同时，证明通道中的离子数量和背景温度对自发发射光谱都有显著影响。研究还表明，外部太赫兹辐射可加速钙通过离子通道的运输。这些结果有望为未来神经学领域中太赫兹波的治疗提供理论依据。
