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近场电纺:关键参数、挑战与应用。

Near-Field Electrospinning: Crucial Parameters, Challenges, and Applications.

机构信息

Department of Biomaterials & Tissue Engineering, Faculty of Biomedical Engineering, Amirkabir University of Technology, Tehran 159163-4311, Iran.

出版信息

ACS Appl Bio Mater. 2022 Feb 21;5(2):394-412. doi: 10.1021/acsabm.1c00944. Epub 2022 Jan 7.

Abstract

Near-field electrospinning (NFES) is a micro- or nanofiber production technology based on jetting molten polymer or polymer solution. Thanks to the programmable collector and nozzle movement, it can generate designed patterns in the presence of an electric field. Despite a few shortcomings of NFES, its high resolution, simplicity, precision, high throughput, reproducibility, and low costs have convinced researchers to employ it for various purposes. Furthermore, as the paradigm of fiber-based structures shifts from random textures toward delicate designs, NFES can bridge the gap between existing inefficient processes and aspired technologies for precise patterning. NFES facilitates the production of ultrafine nanofibers because it can be used to fabricate them in every laboratory. These robust fibers are convenient tools for small and additive manufacturing. As such, NFES is considered a potent additive fabrication technology that facilitates the production of complicated patterns as well. It is suggested that near-field electrospun fibers exhibit outstanding results in various applications, owing to their precise and controllable positioning. Meanwhile, the ongoing development of NFES has yet to reach its climax, making it attractive for further research. In this review, the basic principles of NFES, derivatives, limitations, and applications in nanomanufacturing, tissue engineering, microscale electronics, biosensors, and optics are presented.

摘要

近场电纺(NFES)是一种基于喷射熔融聚合物或聚合物溶液的微/纳米纤维生产技术。由于可编程收集器和喷嘴的运动,它可以在电场存在的情况下产生设计图案。尽管 NFES 存在一些缺点,但它的高分辨率、简单性、精确性、高吞吐量、可重复性和低成本已经说服研究人员将其用于各种目的。此外,随着纤维基结构的范式从随机纹理转向精细设计,NFES 可以弥合现有低效工艺与期望的精确图案化技术之间的差距。NFES 可以促进超细纳米纤维的生产,因为它可以用于在每个实验室中制造它们。这些坚固的纤维是小型和添加剂制造的便捷工具。因此,NFES 被认为是一种强大的添加剂制造技术,也可以促进复杂图案的生产。由于其精确和可控的定位,建议近场电纺纤维在各种应用中表现出出色的结果。同时,NFES 的不断发展尚未达到高潮,因此吸引了进一步的研究。在这篇综述中,介绍了 NFES 的基本原理、衍生物、局限性以及在纳米制造、组织工程、微尺度电子、生物传感器和光学方面的应用。

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