King William E, Bowlin Gary L
Department of Biomedical Engineering, University of Memphis, Memphis, TN 38152, USA.
Department of Biomedical Engineering, University of Tennessee Health Science Center, Memphis, TN 38163, USA.
Polymers (Basel). 2021 Mar 30;13(7):1097. doi: 10.3390/polym13071097.
Near-field electrospinning (NFES) and melt electrowriting (MEW) are the process of extruding a fiber due to the force exerted by an electric field and collecting the fiber before bending instabilities occur. When paired with precise relative motion between the polymer source and the collector, a fiber can be directly written as dictated by preprogrammed geometry. As a result, this precise fiber control results in another dimension of scaffold tailorability for biomedical applications. In this review, biomedically relevant polymers that to date have manufactured fibers by NFES/MEW are explored and the present limitations in direct fiber writing of standardization in published setup details, fiber write throughput, and increased ease in the creation of complex scaffold geometries are discussed.
近场静电纺丝（NFES）和熔体静电书写（MEW）是在电场力作用下挤出纤维，并在弯曲失稳发生之前收集纤维的过程。当聚合物源与收集器之间存在精确的相对运动时，纤维可以按照预先设定的几何形状直接书写。因此，这种精确的纤维控制为生物医学应用带来了支架可定制性的另一个维度。在本综述中，探讨了迄今为止通过NFES/MEW制造纤维的生物医学相关聚合物，并讨论了已发表的设置细节、纤维书写通量以及复杂支架几何形状创建的简易性方面在直接纤维书写标准化方面目前存在的局限性。
