Sumiya H, Ishii H, Fuse H, Matsuzaki O, Shimazaki J
Department of Urology, School of Medicine, Chiba University, Japan.
Urol Int. 1987;42(4):288-91. doi: 10.1159/000281959.
Comparison of the grades classified by Gleason with R-1881 binding which was attributable to total androphilic proteins in tissues was performed in 42 untreated and 13 relapsed prostatic cancers. Increasing malignancy correlated with loss of staining on R-1881 binding when examined both in primary pattern and in individual tumor cell clusters. In relapsed cancer, however, there was no R-1881 binding irrespective of any grades.
在42例未经治疗的前列腺癌和13例复发性前列腺癌中，对Gleason分级与归因于组织中总嗜雄激素蛋白的R-1881结合情况进行了比较。无论是在原发模式还是在单个肿瘤细胞簇中检查，恶性程度增加都与R-1881结合染色的丧失相关。然而，在复发性癌症中，无论分级如何，均未发现R-1881结合。
