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基于深度学习的颞下颌关节关节盘磁共振图像自动分割。

Automated segmentation of articular disc of the temporomandibular joint on magnetic resonance images using deep learning.

机构信息

Department of Orthodontics and Craniofacial Development Biology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, 734-8553, Japan.

Department of Medical System Engineering, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, 734-8553, Japan.

出版信息

Sci Rep. 2022 Jan 7;12(1):221. doi: 10.1038/s41598-021-04354-w.

DOI:10.1038/s41598-021-04354-w
PMID:34997167
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8741780/
Abstract

Temporomandibular disorders are typically accompanied by a number of clinical manifestations that involve pain and dysfunction of the masticatory muscles and temporomandibular joint. The most important subgroup of articular abnormalities in patients with temporomandibular disorders includes patients with different forms of articular disc displacement and deformation. Here, we propose a fully automated articular disc detection and segmentation system to support the diagnosis of temporomandibular disorder on magnetic resonance imaging. This system uses deep learning-based semantic segmentation approaches. The study included a total of 217 magnetic resonance images from 10 patients with anterior displacement of the articular disc and 10 healthy control subjects with normal articular discs. These images were used to evaluate three deep learning-based semantic segmentation approaches: our proposed convolutional neural network encoder-decoder named 3DiscNet (Detection for Displaced articular DISC using convolutional neural NETwork), U-Net, and SegNet-Basic. Of the three algorithms, 3DiscNet and SegNet-Basic showed comparably good metrics (Dice coefficient, sensitivity, and positive predictive value). This study provides a proof-of-concept for a fully automated deep learning-based segmentation methodology for articular discs on magnetic resonance images, and obtained promising initial results, indicating that the method could potentially be used in clinical practice for the assessment of temporomandibular disorders.

摘要

颞下颌关节紊乱通常伴有多种临床表现,包括咀嚼肌和颞下颌关节的疼痛和功能障碍。颞下颌关节紊乱患者关节异常的最重要亚组包括具有不同形式的关节盘移位和变形的患者。在这里,我们提出了一种完全自动化的关节盘检测和分割系统,以支持磁共振成像上颞下颌关节紊乱的诊断。该系统使用基于深度学习的语义分割方法。该研究共纳入了 217 例来自 10 例关节盘前移位患者和 10 例正常关节盘的健康对照者的磁共振图像。这些图像用于评估三种基于深度学习的语义分割方法:我们提出的名为 3DiscNet(使用卷积神经网络检测移位的关节盘)的卷积神经网络编码器-解码器、U-Net 和 SegNet-Basic。在这三种算法中,3DiscNet 和 SegNet-Basic 表现出相当好的指标(Dice 系数、敏感性和阳性预测值)。这项研究为磁共振图像上关节盘的全自动基于深度学习的分割方法提供了概念验证,并获得了有希望的初步结果,表明该方法可能有潜力用于临床实践中评估颞下颌关节紊乱。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb91/8741780/ccffa6771e96/41598_2021_4354_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb91/8741780/be266927c8f5/41598_2021_4354_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb91/8741780/8f054cf60e92/41598_2021_4354_Fig2_HTML.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb91/8741780/d9ae78e2775a/41598_2021_4354_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb91/8741780/ccffa6771e96/41598_2021_4354_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb91/8741780/be266927c8f5/41598_2021_4354_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb91/8741780/8f054cf60e92/41598_2021_4354_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb91/8741780/f202c65953ef/41598_2021_4354_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb91/8741780/89e35cb67c1b/41598_2021_4354_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb91/8741780/d9ae78e2775a/41598_2021_4354_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb91/8741780/ccffa6771e96/41598_2021_4354_Fig6_HTML.jpg

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