Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA.
Autism Center, Texas Children's Hospital, Houston, TX, USA.
J Autism Dev Disord. 2023 Jan;53(1):370-377. doi: 10.1007/s10803-021-05407-9. Epub 2022 Jan 8.
We evaluated the success of a best practice alert (BPA) in recruiting underrepresented families into an autism spectrum disorder research cohort by comparing BPA-response outcomes (Interested, Declined, Enrolled, Dismissed) in pediatric primary care practices (TCPs) serving diverse communities with those of subspecialty clinics. Compared to subspecialty clinics, TCPs had higher proportions of Interested responses for patients with private insurance (60.9% vs. 46.2%), Dismissed responses for patients with public insurance (30.1% vs. 20.0%), and Interested responses for non-white patients (47.7% vs. 33.3%). A targeted BPA can help researchers access more diverse groups and improve equitable representation. However, select groups more often had their alert dismissed, suggesting possible selection bias among some pediatricians regarding who should receive information about study opportunities.
我们评估了最佳实践警报（BPA）在招募代表性不足的家庭参与自闭症谱系障碍研究队列方面的成功，通过比较服务于不同社区的儿科初级保健实践（TCP）与专科诊所的 BPA 响应结果（感兴趣、拒绝、参与、驳回）。与专科诊所相比，私人保险患者的 TCP 有更高比例的感兴趣反应（60.9%对 46.2%），公共保险患者的 TCP 有更高比例的驳回反应（30.1%对 20.0%），非白人患者的 TCP 有更高比例的感兴趣反应（47.7%对 33.3%）。有针对性的 BPA 可以帮助研究人员接触到更多样化的群体，并提高公平代表性。然而，某些群体的警报被驳回的比例更高，这表明一些儿科医生在谁应该收到关于研究机会的信息方面可能存在选择偏见。
