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鼻腔冲洗效率评估仪器和程序的开发。

Development of an apparatus and procedure for evaluating the efficiency of nasal irrigation.

机构信息

Department of Otolaryngology, Beijing Anzhen Hospital, Capital Medical University, Anzhen Road 2, Chaoyang District, Beijing, 100029, People's Republic of China.

Beijing Institute of Heart Lung and Blood Vessel Diseases, Beijing, People's Republic of China.

出版信息

Eur Arch Otorhinolaryngol. 2022 Aug;279(8):3997-4005. doi: 10.1007/s00405-021-07249-8. Epub 2022 Jan 9.

DOI:10.1007/s00405-021-07249-8
PMID:34999922
Abstract

BACKGROUND

Although different methods of nasal irrigation have been utilized, irrigation efficiency in nasal cavities has not been well assessed. The objective of this study was to develop an apparatus and procedure for evaluating the irrigation efficiency and to explore the optimal head position during irrigation.

METHODS

Casts of the left sinonasal cavity from a healthy volunteer were made from high-resolution-computed tomography data using 3D printing with composite materials. An adjustable apparatus that allowed cast fixation at the different head positions was built. The yogurt was used to simulate mucus. The cast with 5 ml yogurt filled around the superior, middle, and inferior turbinate was fixed in six head positions including head tilt 10°, 45°, and 60° forward with or without leaning 30° to the right. The cast was irrigated with 120 ml, 175 ml, and 240 ml dyed water and was video recorded. The irrigation efficiency was calculated based on the weight difference of the cast before and after the irrigation.

RESULTS

Most residual yogurt was located around the superior meatus after the irrigation under different volumes and head positions. The irrigation efficiency of the rinse bottle or the pulsatile device was volume dependent, with the highest irrigation efficiency under 240 ml water. When the left sinonasal cavity was irrigated, the head position of tilt 45° forward with leaning 30° to the right was the optimal head position for these two devices when compared to other positions. The pulsatile device with 240 ml water performed better than the rinse bottle with 240 ml water regarding the irrigation efficiency under the optimal head position (0.8700 ± 0.0138 vs 0.7536 ± 0.0099, p = 0.003).

CONCLUSIONS

The developed apparatus provided a potential method for evaluating the irrigation efficiency. The head position of tilt 45° forward with leaning 30° was suitable for patients to perform the nasal irrigation.

摘要

背景

尽管已经采用了不同的鼻腔冲洗方法,但鼻腔冲洗效率尚未得到很好的评估。本研究的目的是开发一种评估冲洗效率的装置和程序,并探讨冲洗过程中的最佳头部位置。

方法

使用复合材料通过 3D 打印从健康志愿者的左鼻腔鼻窦的高分辨率计算机断层扫描数据制作铸型。构建了一个可调节的装置,允许铸型在不同的头部位置固定。酸奶用于模拟黏液。将充满 5ml 酸奶的铸型固定在六个头部位置,包括头倾斜 10°、45°和 60°前倾,或向右侧倾斜 30°。用 120ml、175ml 和 240ml 染色水冲洗铸型并进行视频记录。根据冲洗前后铸型的重量差异计算冲洗效率。

结果

在不同的体积和头部位置下,冲洗后大部分残留的酸奶都位于上颌窦口周围。冲洗瓶或脉冲式冲洗器的冲洗效率与体积有关,在 240ml 水时冲洗效率最高。当冲洗左鼻腔鼻窦时,与其他位置相比,头前倾 45°向右侧倾斜 30°的位置是这两种装置的最佳头部位置。在最佳头部位置下,240ml 水的脉冲式冲洗器的冲洗效率优于 240ml 水的冲洗瓶(0.8700 ± 0.0138 比 0.7536 ± 0.0099,p=0.003)。

结论

所开发的装置为评估冲洗效率提供了一种潜在的方法。头前倾 45°向右侧倾斜 30°的头部位置适合患者进行鼻腔冲洗。

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本文引用的文献

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Saline nasal irrigation for acute upper respiratory tract infections in infants and children: A systematic review and meta-analysis.婴幼儿急性上呼吸道感染的盐水鼻腔冲洗:一项系统评价和荟萃分析。
Paediatr Respir Rev. 2020 Nov;36:151-158. doi: 10.1016/j.prrv.2019.11.003. Epub 2020 Feb 21.
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EPOS2020: a major step forward.EPOS2020:向前迈出的一大步。
Rhinology. 2020 Feb 1;58(1):1. doi: 10.4193/Rhin20.401.
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Deposition of drugs in the nose and sinuses with an exhalation delivery system vs conventional nasal spray or high-volume irrigation in Draf II/III post-surgical anatomy.
一种新型冲洗装置,与经典冲洗瓶相比,鼻腔冲洗效率更高。
J Otolaryngol Head Neck Surg. 2022 May 3;51(1):19. doi: 10.1186/s40463-022-00575-9.
在 Draf II/III 术后解剖结构中,与传统鼻腔喷雾或大容量冲洗相比,呼气输送系统在鼻腔和鼻窦中的药物沉积。
Rhinology. 2020 Apr 1;58(2):175-183. doi: 10.4193/Rhin18.304.
4
International Consensus Statement on Allergy and Rhinology: Allergic Rhinitis.国际过敏与鼻科学学会共识声明:变应性鼻炎。
Int Forum Allergy Rhinol. 2018 Feb;8(2):108-352. doi: 10.1002/alr.22073.