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急性颅内颈内动脉闭塞应用球囊引导导管连续近端血流阻断的取栓支架(RTRS)重复血栓切除术的初步临床经验。

Initial Clinical Experience of Repeat Thrombectomy with a Retrieval Stent (RTRS) with Continuous Proximal Flow Arrest by Balloon Guide Catheter for Acute Intracranial Carotid Occlusion.

机构信息

Department of Neurointervention, Zhangzhou Affiliated Hospital of Fujian Medical University, Fujian, China.

出版信息

Behav Neurol. 2021 Dec 31;2021:7607324. doi: 10.1155/2021/7607324. eCollection 2021.

DOI:10.1155/2021/7607324
PMID:35003387
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8741371/
Abstract

BACKGROUND

Balloon guide catheters (BGCs) have good performance in terms of radiological outcomes in acute ischemic thrombectomy. It is not uncommon for BGCs to be blocked by thrombi, especially in cases with acute intracranial internal carotid artery (ICA) occlusion. Our initial experience using repeat thrombectomy with a retrieval stent (RTRS) with continuous proximal flow arrest by BGC for acute intracranial ICA occlusion is presented.

METHODS

In patients with acute intracranial ICA occlusion treated with RTRS, clinical data, including the National Institutes of Health Stroke Scale (NIHSS) score at admission and modified Rankin Scale (mRS) score at 90 days, and procedural data, including the Extended treatment in Cerebral Infarction (eTICI) score, procedural time, and complications, were analyzed.

RESULTS

Thirty-two consecutive patients (12 men (37.5%); mean age: 73 years) were treated with RTRS using a BGC. The median NIHSS score was 19. The median puncture-to-reperfusion time was 46 minutes (range: 22-142 minutes). All patients were successfully revascularized; eTICI 2c or better recanalization was achieved in 30 (93.8%) patients. No procedure-related complications or symptomatic intracranial hemorrhage occurred. Two cases (6.3%) had distal emboli, but none had emboli to the anterior cerebral artery. Fourteen patients (43.8%) achieved a good outcome with an mRS score of 0-2 at 90 days, and 8 patients (25.0%) died.

CONCLUSIONS

In patients with intracranial ICA occlusion, RTRS with proximal flow arrest by BGC is effective and safe, achieving good clinical and angiographic outcomes. This method may reduce the incidence of distal emboli in thrombectomy with stent retrievers.

摘要

背景

球囊引导导管(BGC)在急性缺血性血栓切除术的影像学结果方面表现良好。BGC 被血栓堵塞并不罕见,特别是在急性颅内颈内动脉(ICA)闭塞的情况下。我们介绍了一种使用重复血栓切除术和带有连续近端血流阻断的回收支架(RTRS)治疗急性颅内 ICA 闭塞的初步经验。

方法

在接受 RTRS 治疗的急性颅内 ICA 闭塞患者中,分析了包括入院时国立卫生研究院卒中量表(NIHSS)评分和 90 天时改良 Rankin 量表(mRS)评分在内的临床数据,以及包括扩展治疗脑梗死(eTICI)评分、手术时间和并发症在内的手术数据。

结果

32 例连续患者(男性 12 例(37.5%);平均年龄:73 岁)接受 BGC 辅助的 RTRS 治疗。NIHSS 评分中位数为 19。穿刺至再灌注时间中位数为 46 分钟(范围:22-142 分钟)。所有患者均成功再通;30 例(93.8%)患者达到 eTICI 2c 或更好的再通。无手术相关并发症或症状性颅内出血。2 例(6.3%)发生远端栓塞,但无大脑前动脉栓塞。14 例(43.8%)患者在 90 天时 mRS 评分为 0-2,取得良好预后,8 例(25.0%)患者死亡。

结论

在颅内 ICA 闭塞患者中,近端血流阻断的 BGC 辅助 RTRS 是有效且安全的,可获得良好的临床和血管造影结果。这种方法可能会降低支架取栓术中远端栓塞的发生率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f614/8741371/ea27690ea9f0/BN2021-7607324.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f614/8741371/5fe4ef286d21/BN2021-7607324.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f614/8741371/ea27690ea9f0/BN2021-7607324.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f614/8741371/5fe4ef286d21/BN2021-7607324.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f614/8741371/ea27690ea9f0/BN2021-7607324.002.jpg

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