Rosai J
Am J Clin Pathol. 1978 May;69(5):475-81. doi: 10.1093/ajcp/69.5.475.
A case of myospherulosis of paranasal sinuses similar in appearance to those recently seen in St. Louis, Missouri, was examined to ascertain the nature of the sac-like structures seen in this disease. The morphologic features of these formations and their positivity with stains for hemoglobin, peroxidase, and lipofuscin strongly suggest that they represent collections of erythrocytes altered by a foreign substance. This interpretation was confirmed by experimental production of these structures by the action of tetracycline ointment on a pure preparation of human erythrocytes.
对一例鼻窦肌球孢子菌病进行了检查，该病例外观与最近在密苏里州圣路易斯市发现的病例相似，以确定在这种疾病中所见囊状结构的性质。这些结构的形态特征以及它们对血红蛋白、过氧化物酶和脂褐素染色的阳性反应强烈表明，它们代表了被异物改变的红细胞聚集物。通过四环素软膏作用于纯人类红细胞制剂实验性产生这些结构，证实了这一解释。
