在用接触致敏剂免疫后，小鼠局部淋巴结中淋巴因子激活的杀伤细胞（LAK）活性增强。
Increased lymphokine activated killer (LAK) activity in the regional lymph nodes of mice following immunization with contact sensitizing agents.
作者信息
Gao L Q, Asherson G L, Malkovsky M
机构信息
Division of Immunological Medicine, Clinical Research Centre, Harrow, UK.
出版信息
Clin Exp Immunol. 1987 Oct;70(1):217-21.
Abstract
The regional lymph nodes of mice show increased IL-2 activated killer (LAK) activity following immunization with the contact sensitizing agents, 'oxazolone' and picryl chloride. This is best elicited with 500 mu/ml human recombinant IL-2 and can be demonstrated with both YAC-1 and K562 targets. There is also a lesser increase in NK activity.
摘要
在用接触致敏剂“恶唑酮”和苦味酸氯化物免疫后，小鼠的局部淋巴结显示出白细胞介素-2激活的杀伤细胞（LAK）活性增加。这在用500微克/毫升人重组白细胞介素-2时最易引发，并且用YAC-1和K562靶细胞均可证实。自然杀伤细胞（NK）活性也有较小程度的增加。
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