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比较 COVID-19 住院和非住院老年患者的临床特征和死亡率:回顾性观察研究。

Comparing the Clinical Characteristics and Mortality of Residential and Non-Residential Older People with COVID-19: Retrospective Observational Study.

机构信息

Health Promotion in Rural Areas Research Group, Gerència Territorial de la Catalunya Central, Institut Català de la Salut, 08772 St. Fruitós de Bages, Spain.

Unitat de Suport a la Recerca de la Catalunya Central, Fundació Institut Universitari per a la Recerca a l'Atenció Primària de Salut Jordi Gol i Gurina, 08772 St. Fruitós de Bages, Spain.

出版信息

Int J Environ Res Public Health. 2022 Jan 2;19(1):483. doi: 10.3390/ijerph19010483.

Abstract

Nursing homes have accounted for a significant part of SARS-CoV-2 mortality, causing great social alarm. Using data collected from electronic medical records of 1,319,839 institutionalised and non-institutionalised persons ≥ 65 years, the present study investigated the epidemiology and differential characteristics between these two population groups. Our results showed that the form of presentation of the epidemic outbreak, as well as some risk factors, are different among the elderly institutionalised population with respect to those who are not. In addition to a twenty-fold increase in the rate of adjusted mortality among institutionalised individuals, the peak incidence was delayed by approximately three weeks. Having dementia was shown to be a risk factor for death, and, unlike the non-institutionalised group, neither obesity nor age were shown to be significantly associated with the risk of death among the institutionalised. These differential characteristics should be able to guide the actions to be taken by the health administration in the event of a similar infectious situation among institutionalised elderly people.

摘要

养老院在 SARS-CoV-2 死亡率中占很大比例,引起了极大的社会恐慌。本研究使用从 1319839 名≥65 岁的住院和非住院人群的电子病历中收集的数据,调查了这两个人群的流行病学和差异特征。我们的结果表明,与非住院人群相比,住院老年人群的疫情爆发形式以及一些风险因素有所不同。除了住院人群的调整死亡率增加了二十倍之外,发病高峰还延迟了大约三周。痴呆是死亡的危险因素,与非住院人群不同,肥胖和年龄都与住院人群的死亡风险没有显著相关性。这些差异特征应该能够指导卫生行政部门在住院老年人中发生类似传染病时采取行动。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/543c/8744689/41b88272fb4b/ijerph-19-00483-g001.jpg

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