Department of Chemistry, College of Chemistry and Materials Engineering, Beijing Technology and Business University, Beijing 100048, P. R. China.
ACS Appl Bio Mater. 2021 Jan 18;4(1):370-386. doi: 10.1021/acsabm.0c01395. Epub 2020 Dec 18.
Infectious deaths due to drug resistance of pathogens caused by the abuse of antibiotics have seriously endangered public health in the world. Therefore, it is urgent to develop diversified methods for rapid detection of pathogens and antimicrobial drugs that are not prone to develop resistance. Conjugated polymers (CPs) are macromolecular compounds composed of many luminescent units through covalent bond. They have high molar extinction coefficient and strong light absorption capacity. In addition, they have good photo stability and excellent biocompatibility. In recent years, conjugated polymer nanomaterials (CPNs) have stimulated the research enthusiasm of many researchers because of the materials' small size, high fluorescence intensity, and easy modification. This article reviews the recent research progress of conjugated polymer nanomaterials in the detection and killing of pathogenic microbes.
由于抗生素滥用导致病原体耐药性引起的传染性死亡已严重威胁到全球公众健康。因此，迫切需要开发多样化的方法来快速检测病原体和不易产生耐药性的抗菌药物。共轭聚合物（CPs）是由许多通过共价键连接的发光单元组成的高分子化合物。它们具有高摩尔消光系数和强吸光能力。此外，它们具有良好的光稳定性和优异的生物相容性。近年来，共轭聚合物纳米材料（CPNs）由于其尺寸小、荧光强度高、易于修饰等特点，激发了许多研究人员的研究热情。本文综述了近年来共轭聚合物纳米材料在检测和杀灭致病微生物方面的研究进展。
