Department of Chemical, Biological & Macromolecular Sciences, S. N. Bose National Centre for Basic Sciences, Block-JD, Sector-III, Salt Lake City, Kolkata 700106, India.
Technical Research Centre, S. N. Bose National Centre for Basic Sciences, Block-JD, Sector-III, Salt Lake City, Kolkata 700106, India.
ACS Appl Bio Mater. 2021 Apr 19;4(4):2863-2885. doi: 10.1021/acsabm.0c01480. Epub 2021 Mar 10.
The significant role of a vesicle is well recognized; however, only lately has the advancement in biomedical applications started to uncover their usefulness. Although the concept of vesicles originates from cell biology, it later transferred to chemistry and material science to develop nanoscale artificial vesicles for biomedical applications. Herein, we examine different synthetic and biological vesicles and their applications in the biomedical field in general. As our understanding of biological vesicles increases, more suitable biomimicking synthetic vesicles will be developed. The comparative discussion between synthetic and natural vesicles for biomedical applications is a relevant topic, and we envision this could enable the development of a proper approach to realize the next-generation treatment goals.
囊泡的重要作用已得到广泛认可；然而，直到最近，生物医学应用的发展才开始揭示它们的有用性。尽管囊泡的概念起源于细胞生物学，但后来它被转移到化学和材料科学领域，以开发用于生物医学应用的纳米级人工囊泡。在此，我们研究了不同的合成和生物囊泡及其在生物医学领域的一般应用。随着我们对生物囊泡的理解不断加深，将开发出更合适的仿生合成囊泡。合成囊泡与生物囊泡在生物医学应用方面的比较讨论是一个相关的话题，我们设想这可能有助于开发出一种合适的方法来实现下一代治疗目标。
