Suppr超能文献

[卡米诺霉素在乳腺癌中的研究]

[Carminomycin study in breast cancer].

作者信息

Lichinitser M R, Assekritova I V, Gorbunova V A, Arseriĭ S A, Vaarik Kh M

出版信息

Antibiotiki. 1978 May;23(5):453-7.

PMID:350145
Abstract

Karminomycin was used for the treatment of cases with disseminated cancer of the mammary gland in doses of 5 mg/m2 of the body surface intravenously every day for 5 days (15 patients) or 6 mg/m2 twice a week for 2-3 weeks (30 patients). Partial remission or diminution of the tumor size at least by 50 per cent was observed in 26 and 17 per cent of the patients respectively. The remission duration was from 2 to 6 months. With the use of the shortperiod scheme the frequency of the direct side reactions increased. Leucopenia as a side effect was registered in 100 and 40 per cent of the patients and thrombocytopenia was registered in 18 and 3 per cent of the cases respectively.

摘要

卡米诺霉素用于治疗弥漫性乳腺癌患者,剂量为每天5毫克/平方米体表面积,静脉注射,共5天(15例患者),或每周两次,每次6毫克/平方米,持续2 - 3周(30例患者)。分别在26%和17%的患者中观察到部分缓解或肿瘤大小至少缩小50%。缓解期为2至6个月。采用短期方案时,直接副作用的发生率增加。分别有100%和40%的患者出现白细胞减少这一副作用,18%和3%的病例出现血小板减少。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验