College of Chemistry and Chemical Engineering, Liaoning Normal University, Huanghe Road 850#, Dalian 116029, PR China.
College of Chemistry and Chemical Engineering, Liaoning Normal University, Huanghe Road 850#, Dalian 116029, PR China.
Spectrochim Acta A Mol Biomol Spectrosc. 2022 Apr 5;270:120784. doi: 10.1016/j.saa.2021.120784. Epub 2022 Jan 3.
Two remarkablely fluorimetric probes were developed to rapidly detect 2,4,6-trinitrophenol (TNP). With the help of density functional theory (DFT) calculations, we confirmed that using 1,3,4-thiadiazole skeleton as recognition group and coumarin unit as fluorophore would show excellent application prospects in terms of TNP detection. The probes LK-1 and LK-2 displayed green and orange emission with fluorescence quenching yield as high as 83.7% and 75.1% in solution. Further evaluation demonstrated that they display outstanding selectivity and sensitivity for rapid and visual detection of TNP. Both fluorescent color and fluorescence emission spectrum had significant changes and these phenomena could easily observe via naked-eye and analytical instrument. The detection limits of them were 97 nM and 71 nM. What's more, application in real water samples and solid phase paper tests illustrated the practical significance of detection of TNP.
开发了两种非常荧光探针，用于快速检测 2,4,6-三硝基苯酚（TNP）。借助密度泛函理论（DFT）计算，我们证实，使用 1,3,4-噻二唑骨架作为识别基团和香豆素单元作为荧光团，在 TNP 检测方面将具有极好的应用前景。探针 LK-1 和 LK-2 在溶液中表现出绿色和橙色发射，荧光猝灭产率高达 83.7%和 75.1%。进一步评估表明，它们对 TNP 的快速、可视化检测表现出出色的选择性和灵敏度。荧光颜色和荧光发射光谱都有明显的变化，这些现象可以通过肉眼和分析仪器轻易观察到。它们的检测限分别为 97 nM 和 71 nM。更重要的是，在实际水样和固相纸测试中的应用说明了 TNP 检测的实际意义。
