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椎板后阻滞用于腰椎后路椎间盘切除术后无阿片类药物麻醉及加速康复:一项随机对照研究。

Retrolaminar block for opioid-free anaesthesia and enhanced recovery after posterior lumbar discectomy: A randomised controlled study.

作者信息

Kamel Alshaimaa A F, Fahmy Ahmed M, Medhat Marwa M, Ali Elmesallamy Wael A E, Salem Dina A E

机构信息

Department of Anaesthesia, Intensive Care and Pain Management, Faculty of Human Medicine, Zagazig University, Alsharkia, Egypt.

出版信息

Indian J Anaesth. 2024 Mar;68(3):261-266. doi: 10.4103/ija.ija_773_23. Epub 2024 Feb 22.

Abstract

BACKGROUND AND AIMS

Intraoperative regional analgesia and enhanced recovery are standard care models aimed at reducing perioperative opioid use following spine surgeries. This study aimed to examine the analgesic effect of retrolaminar block in promoting recovery and pain relief after posterior lumbar discectomy.

METHODS

The patients undergoing elective posterior lumbar discectomy were randomised into the retrolaminar group (n = 36) (received an intra-operative bilateral retrolaminar block with 15 mL of bupivacaine 0.25%, 2 mL (8 mg) of dexamethasone, and 2 mL of magnesium sulphate 10% (200 mg) on each side) and control group (n = 36) (received standard general anaesthesia). Primary outcomes were recovery time (time from isoflurane discontinuation to the first response to verbal command) and time to discharge (time from admission to the post-anaesthesia care unit (PACU) to discharge from the PACU, when Aldrete score was ≥9). values < 0.05 were considered statistically significant.

RESULTS

The extubation, recovery, and discharge times were significantly shorter in the retrolaminar group compared to the control group ( < 0.001). Postoperative pain scores were significantly lower in the retrolaminar group for up to 8 h compared to only 2 h in the control group ( < 0.001). The time to first administration of ketorolac post-operatively was significantly longer in the retrolaminar group compared to the control group ( < 0.001). The total consumption of ketorolac post-operatively was significantly reduced in the retrolaminar group compared to the control group ( < 0.001).

CONCLUSION

Intra-operative retrolaminar block is an easy and effective opioid-free regional anaesthesia technique that improves recovery after posterior lumbar discectomy.

摘要

背景与目的

术中区域镇痛和加速康复是旨在减少脊柱手术后围手术期阿片类药物使用的标准护理模式。本研究旨在探讨椎板后阻滞在促进腰椎后路椎间盘切除术后恢复和缓解疼痛方面的镇痛效果。

方法

将择期行腰椎后路椎间盘切除术的患者随机分为椎板后组(n = 36)(术中双侧椎板后阻滞,每侧注射15 mL 0.25%布比卡因、2 mL(8 mg)地塞米松和2 mL 10%硫酸镁(200 mg))和对照组(n = 36)(接受标准全身麻醉)。主要结局指标为恢复时间(从停用异氟烷到首次对言语指令做出反应的时间)和出院时间(从进入麻醉后护理单元(PACU)到Aldrete评分≥9分后从PACU出院的时间)。P值<0.05被认为具有统计学意义。

结果

与对照组相比,椎板后组的拔管、恢复和出院时间明显缩短(P<0.001)。椎板后组术后疼痛评分在长达8小时内显著低于对照组,而对照组仅在2小时内显著低于椎板后组(P<0.001)。与对照组相比,椎板后组术后首次使用酮咯酸的时间明显延长(P<0.001)。与对照组相比,椎板后组术后酮咯酸的总消耗量显著减少(P<0.001)。

结论

术中椎板后阻滞是一种简单有效的无阿片类区域麻醉技术,可改善腰椎后路椎间盘切除术后的恢复情况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8693/10926343/8ff970a22c91/IJA-68-261-g001.jpg

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