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艾滋病毒-1 遗传多样性对艾滋病疫苗开发的挑战:回顾性文献计量分析。

HIV-1 genetic diversity a challenge for AIDS vaccine development: a retrospective bibliometric analysis.

机构信息

School of Medicine, Nankai University, Tianjin, China.

State Key Laboratory for Infectious Disease Prevention and Control, National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.

出版信息

Hum Vaccin Immunother. 2022 Dec 31;18(1):2014733. doi: 10.1080/21645515.2021.2014733. Epub 2022 Jan 11.

DOI:10.1080/21645515.2021.2014733
PMID:35016590
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8973384/
Abstract

BACKGROUND

Despite recent advances in human immunodeficiency virus-1 (HIV-1) prevention, a fast, safe, and effective vaccine will probably be necessary to end the HIV/AIDS pandemic. This study was conducted to evaluate global research trends and map the key bibliometric indices in HIV-1 genetic diversity from 1998 to 2021.

METHODS

A comprehensive online search was conducted in the Web of Science Core Collection database to retrieve published literature on HIV-1 genetic diversity. Key bibliometric indicators were calculated and evaluated using HistCite, Bibliometrix: An R-tool, and VOSviewer software for windows.

RESULTS

A total of 2,060 documents written by 9,201 authors and published in 250 journals were included in the final analysis. Year 2012 was the most productive year with 121 (5.87%) publications. The most prolific author was Shao Yiming (n = 74, 3.59%) from Chinese Center for Disease Control and Prevention. The United States of America was the highly contributing and influential country (n = 681, 33.05%). was the most productive journal (n = 562, 27.2%). Network visualization shows that HIV-1 was the most widely used author keyword.

CONCLUSION

This study provides global research trends and detailed information on HIV-1 genetic diversity. The amount of scientific literature on HIV-1 genetic diversity research has rapidly increased in the last two decades. The maximum number of articles on HIV-1 genetic diversity was published in developed countries; therefore, a scientific research collaboration among researchers and institutes in low-income countries should be promoted and supported.

摘要

背景

尽管人类免疫缺陷病毒 1 (HIV-1) 的预防技术近年来取得了进展,但为了终结 HIV/AIDS 大流行,可能仍需要一种快速、安全、有效的疫苗。本研究旨在评估 1998 年至 2021 年期间 HIV-1 遗传多样性的全球研究趋势,并绘制关键的计量学指标图谱。

方法

在 Web of Science 核心合集数据库中进行了全面的在线检索,以检索有关 HIV-1 遗传多样性的已发表文献。使用 HistCite、Bibliometrix:一个 R 工具和 VOSviewer 软件对关键的计量学指标进行了计算和评估。

结果

共纳入最终分析的 2060 篇文献,由 9201 名作者撰写,发表在 250 种期刊上。2012 年是最具生产力的一年,发表了 121 篇(5.87%)论文。最具影响力的作者是来自中国疾病预防控制中心的邵一鸣(n=74,3.59%)。美国是贡献最大和最有影响力的国家(n=681,33.05%)。《柳叶刀》是最具生产力的期刊(n=562,27.2%)。网络可视化显示,HIV-1 是使用最广泛的作者关键词。

结论

本研究提供了 HIV-1 遗传多样性的全球研究趋势和详细信息。过去 20 年来,HIV-1 遗传多样性研究的科学文献数量迅速增加。关于 HIV-1 遗传多样性的文章数量最多的是在发达国家发表的;因此,应该促进和支持低收入国家的研究人员和机构之间的科学研究合作。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e6d/8973384/e51a0103cf94/KHVI_A_2014733_F0007_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e6d/8973384/a7901ba96d6f/KHVI_A_2014733_F0001_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e6d/8973384/b6c20d953b23/KHVI_A_2014733_F0002_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e6d/8973384/4b14bcc89792/KHVI_A_2014733_F0003_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e6d/8973384/261ec905f526/KHVI_A_2014733_F0004_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e6d/8973384/74ce5253fd86/KHVI_A_2014733_F0005_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e6d/8973384/e93aaab1ccb2/KHVI_A_2014733_F0006_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e6d/8973384/e51a0103cf94/KHVI_A_2014733_F0007_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e6d/8973384/a7901ba96d6f/KHVI_A_2014733_F0001_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e6d/8973384/b6c20d953b23/KHVI_A_2014733_F0002_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e6d/8973384/4b14bcc89792/KHVI_A_2014733_F0003_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e6d/8973384/261ec905f526/KHVI_A_2014733_F0004_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e6d/8973384/74ce5253fd86/KHVI_A_2014733_F0005_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e6d/8973384/e93aaab1ccb2/KHVI_A_2014733_F0006_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e6d/8973384/e51a0103cf94/KHVI_A_2014733_F0007_OC.jpg

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