• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

使用多层螺旋计算机断层扫描和三维打印模型评估腭裂患者二期牙槽骨移植的长期稳定性:一项前瞻性研究。

Evaluation of Long-term Stability of Secondary Alveolar Bone Grafts in Cleft Palate Patients Using Multislice Computed Tomography and Three-Dimensional Printed Models: A Prospective Study.

作者信息

Palankar Venkatesh, Sattur Atul, Palankar Aditi, Rajeswari S Raja, Thakur Srinath, Desai Anil Kumar

机构信息

Department of Orthodontics and Dentofacial Orthopaedics, SDM College of Dental Sciences and Hospital, Dharwad, Karnataka, India.

Department of Oral Medicine and Radiology, SDM College of Dental Sciences and Hospital, Dharwad, Karnataka, India.

出版信息

J Pharm Bioallied Sci. 2021 Nov;13(Suppl 2):S1496-S1500. doi: 10.4103/jpbs.jpbs_265_21. Epub 2021 Nov 10.

DOI:10.4103/jpbs.jpbs_265_21
PMID:35018017
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8687034/
Abstract

AIM

Three-dimensional (3D) printed models are contemporary volumetric bone graft assessment technique for secondary alveolar bone grafting (SABG) in cleft lip and palate (CLP) patients. The study aimed at evaluation of long-term stability of iliac autograft in SABG using multislice computed tomography (CT) and 3D-printed model-based volumetric analysis.

MATERIALS AND METHODS

Twenty-eight patients were included in this prospective clinical study. CT image (T1) was taken after orthodontic maxillary expansion, correlating with the presurgical image. Furthermore, 3D-printed model was prepared, and volumetric assessment of graft needed was ascertained with water displacement technique. SABG was carried on with the anterior iliac crest autografting procedure. After 1-year follow-up, postoperative CT analysis (T2) was followed upon.

RESULTS

The stability of bone graft at the 1-year postoperative was found to be 43.74% with mean bone loss of 56.26% (95% confidence interval; < 0.005). The moderate scale of CLP cases has shown statistically significant bone stability compared to that of severe and mild cases. Furthermore, the 3D-printed model has shown a significant difference to that of T1 CT imaging ( < 0.005).

CONCLUSION

Within the limitations of the study, it seems appropriate to conclude that 3D-printed models serves as better reference than CT imaging in the context of planning and execution of precise bone grafting in SABG.

摘要

目的

三维(3D)打印模型是唇腭裂(CLP)患者二期牙槽骨植骨(SABG)的当代容积性骨移植评估技术。本研究旨在使用多层计算机断层扫描(CT)和基于3D打印模型的容积分析评估SABG中髂骨自体骨移植的长期稳定性。

材料与方法

本前瞻性临床研究纳入28例患者。正畸上颌扩弓后拍摄CT图像(T1),与术前图像进行对比。此外,制备3D打印模型,并采用排水法确定所需移植骨的容积评估。采用髂前嵴自体骨移植术进行SABG。1年随访后,进行术后CT分析(T2)。

结果

术后1年骨移植的稳定性为43.74%,平均骨丢失率为56.26%(95%置信区间;<0.005)。与重度和轻度唇腭裂病例相比,中度唇腭裂病例的骨稳定性具有统计学意义。此外,3D打印模型与T1 CT成像显示出显著差异(<0.005)。

结论

在本研究的局限性范围内,可以得出结论,在SABG精确骨移植的规划和实施方面,3D打印模型比CT成像更适合作为参考。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb8f/8687034/fbe3a674bb92/JPBS-13-1496-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb8f/8687034/c734c69bef58/JPBS-13-1496-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb8f/8687034/fbe3a674bb92/JPBS-13-1496-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb8f/8687034/c734c69bef58/JPBS-13-1496-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb8f/8687034/fbe3a674bb92/JPBS-13-1496-g002.jpg

相似文献

1
Evaluation of Long-term Stability of Secondary Alveolar Bone Grafts in Cleft Palate Patients Using Multislice Computed Tomography and Three-Dimensional Printed Models: A Prospective Study.使用多层螺旋计算机断层扫描和三维打印模型评估腭裂患者二期牙槽骨移植的长期稳定性:一项前瞻性研究。
J Pharm Bioallied Sci. 2021 Nov;13(Suppl 2):S1496-S1500. doi: 10.4103/jpbs.jpbs_265_21. Epub 2021 Nov 10.
2
The Effects of Maxillary Expansion on Late Alveolar Bone Grafting in Patients With Unilateral Cleft Lip and Palate.上颌扩弓对单侧唇腭裂患者晚期牙槽骨植骨的影响。
J Oral Maxillofac Surg. 2019 Mar;77(3):607-614. doi: 10.1016/j.joms.2018.07.022. Epub 2018 Jul 27.
3
Current methods for secondary alveolar bone grafting assessment in cleft lip and palate patients - A systematic review.目前评估唇腭裂患者二次牙槽骨移植的方法 - 系统综述。
J Craniomaxillofac Surg. 2019 Apr;47(4):578-585. doi: 10.1016/j.jcms.2019.01.013. Epub 2019 Jan 17.
4
Comparison of tooth development stage of the maxillary anterior teeth before and after secondary alveolar bone graft: Unilateral cleft lip and alveolus vs unilateral cleft lip and palate.二次牙槽骨植骨前后上颌前牙牙齿发育阶段的比较:单侧唇腭裂与单侧唇裂合并牙槽突裂。
Angle Orthod. 2014 Nov;84(6):989-94. doi: 10.2319/011014-38.1. Epub 2014 Apr 15.
5
Prospective analysis of secondary alveolar bone grafting using computed tomography.使用计算机断层扫描对二期牙槽骨移植的前瞻性分析。
J Oral Maxillofac Surg. 2000 Nov;58(11):1241-9; discussion 1250. doi: 10.1053/joms.2000.16623.
6
Mind the Gap: Alveolar Bone Graft Revision in the Era of Computed Tomography.注意间隙:计算机断层扫描时代的牙槽骨移植修复。
Cleft Palate Craniofac J. 2022 Feb;59(2):246-253. doi: 10.1177/10556656211002689. Epub 2021 Apr 1.
7
Presurgical and postsurgical orthodontics are associated with superior secondary alveolar bone grafting outcomes.术前和术后正畸与更好的二期牙槽骨植骨效果相关。
J Craniomaxillofac Surg. 2015 Jun;43(5):717-23. doi: 10.1016/j.jcms.2015.03.005. Epub 2015 Mar 14.
8
Review of secondary alveolar cleft repair.继发牙槽裂修复的综述。
Ann Maxillofac Surg. 2013 Jan;3(1):46-50. doi: 10.4103/2231-0746.110083.
9
Influence of bone-anchored maxillary protraction on secondary alveolar bone graft status in unilateral complete cleft lip and palate.骨锚定上颌骨前牵引对单侧完全性唇腭裂患者二次牙槽骨骨移植状况的影响。
Am J Orthod Dentofacial Orthop. 2020 Nov;158(5):731-737. doi: 10.1016/j.ajodo.2019.10.021. Epub 2020 Sep 16.
10
Eruption path of permanent maxillary canines after secondary alveolar bone graft in patients with nonsyndromic complete unilateral cleft lip and palate.非综合征性完全性单侧唇腭裂患者二期牙槽骨植骨后上颌恒尖牙的萌出路径
Am J Orthod Dentofacial Orthop. 2022 May;161(5):e416-e428. doi: 10.1016/j.ajodo.2021.06.019. Epub 2022 Mar 5.

引用本文的文献

1
In Vitro Evaluation of Accuracy of CBCT-Derived Volumes in Maxillary Defects: Effects of kVp, Device, and Software.锥形束计算机断层扫描(CBCT)衍生体积在上颌骨缺损中准确性的体外评估:千伏峰值(kVp)、设备和软件的影响
Diagnostics (Basel). 2025 May 14;15(10):1247. doi: 10.3390/diagnostics15101247.
2
A New and Validated Computed Tomography-Based Method for Measurement of Facial Fat Volume.一种基于计算机断层扫描的新型且经过验证的面部脂肪体积测量方法。
Aesthetic Plast Surg. 2025 Mar 3. doi: 10.1007/s00266-025-04769-0.

本文引用的文献

1
A novel accurate volumetric analysis protocol for evaluating secondary alveolar cleft reconstruction.一种用于评估二次牙槽裂重建的新型精确容积分析方案。
J Craniomaxillofac Surg. 2020 Jul;48(7):632-637. doi: 10.1016/j.jcms.2020.02.015. Epub 2020 Mar 2.
2
A Novel Method to Calculate the Volume of Alveolar Cleft Defect Before Surgery.一种术前计算牙槽嵴裂缺损体积的新方法。
J Craniofac Surg. 2018 Mar;29(2):342-346. doi: 10.1097/SCS.0000000000004181.
3
Analyzing the teeth next to the alveolar cleft: Examination and treatment proposal prior to bone grafting based on three-dimensional versus two-dimensional diagnosis-A diagnostic study.
分析牙槽裂旁的牙齿:基于三维与二维诊断的骨移植前检查与治疗建议——一项诊断研究。
J Craniomaxillofac Surg. 2017 Aug;45(8):1272-1277. doi: 10.1016/j.jcms.2017.05.024. Epub 2017 Jun 3.
4
A new method of volumetric assessment of alveolar bone grafting for cleft patients using cone beam computed tomography.一种使用锥形束计算机断层扫描对腭裂患者牙槽骨移植进行容积评估的新方法。
Oral Surg Oral Med Oral Pathol Oral Radiol. 2017 Aug;124(2):e171-e182. doi: 10.1016/j.oooo.2017.04.003. Epub 2017 Apr 19.
5
A novel semi-automatic segmentation protocol for volumetric assessment of alveolar cleft grafting procedures.一种用于牙槽裂植骨手术体积评估的新型半自动分割方案。
J Craniomaxillofac Surg. 2017 May;45(5):685-689. doi: 10.1016/j.jcms.2017.02.018. Epub 2017 Feb 24.
6
Volumetric assessment of alveolar clefts: a literature review.肺泡裂容积评估:文献综述。
J Oral Pathol Med. 2017 Sep;46(8):569-573. doi: 10.1111/jop.12548. Epub 2017 Jan 28.
7
Volumetric Analysis of Alveolar Bone Defect Using Three-Dimensional-Printed Models Versus Computer-Aided Engineering.使用三维打印模型与计算机辅助工程对牙槽骨缺损进行体积分析。
J Craniofac Surg. 2017 Mar;28(2):383-386. doi: 10.1097/SCS.0000000000003301.
8
Difference in the Surgical Outcome of Unilateral Cleft Lip and Palate Patients with and without Pre-Alveolar Bone Graft Orthodontic Treatment.接受和未接受牙槽骨植骨正畸治疗的单侧唇腭裂患者手术结果的差异。
Sci Rep. 2016 Apr 4;6:23597. doi: 10.1038/srep23597.
9
Comparison of different methods to assess alveolar cleft defects in cone beam CT images.锥形束CT图像中评估牙槽嵴裂缺损的不同方法比较。
Dentomaxillofac Radiol. 2016;45(2):20150332. doi: 10.1259/dmfr.20150332. Epub 2015 Dec 9.
10
Effect of Secondary Alveolar Bone Grafting on the Maxillary Growth: Unilateral Versus Bilateral Cleft Lip and Palate Patients.二期牙槽骨植骨对上颌骨生长的影响:单侧与双侧唇腭裂患者对比
J Craniofac Surg. 2015 Oct;26(7):2128-32. doi: 10.1097/SCS.0000000000002133.