糖尿病患者血清高敏C反应蛋白、尿白蛋白与肌酐比值及血脂谱的相关性评估
Assessment of Correlation of Serum High-Sensitive C-Reactive Protein, Urinary Albumin-to-Creatinine Ratio, and Lipid Profile in Diabetics.
作者信息
Kumari Shweta, Singh Beena
机构信息
Department of Biochemistry, KGMU, Lucknow, Uttar Pradesh, India.
Department of Biochemistry, Career Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.
出版信息
J Pharm Bioallied Sci. 2021 Nov;13(Suppl 2):S1569-S1572. doi: 10.4103/jpbs.jpbs_290_21. Epub 2021 Nov 10.
BACKGROUND
This study aimed to measure the level of serum high-sensitive C-reactive protein (hs CRP), urinary albumin-to-creatinine ratio (ACR), lipid profile, and their association in diabetics.
METHODOLOGY
One hundred and fifty diabetic patients were classified into three groups of 50 each. Group I were newly diagnosed with <5 years of diabetes, Group II were those having 5-10 years of diabetes, and Group III were diabetics with more than 10 years of diabetes. Lipid profile, hs-CRP level, and ACR were measured.
RESULTS
There was a correlation between hS CRP and ACR and triglyceride in Group I, hS CRP with ACR and triglyceride in Group I. In group II hS CRP showed significant correlation with ACR whereas in Group III significant correlation was observed with ACR, low density lipoprotein (LDL) and cholesterol.
CONCLUSION
The level of hS CRP and ACR was found to be higher in patients with a longer duration of diabetes.
背景
本研究旨在测量糖尿病患者血清高敏C反应蛋白（hs CRP）、尿白蛋白与肌酐比值（ACR）、血脂水平及其相关性。
方法
150例糖尿病患者被分为三组，每组50例。第一组为新诊断糖尿病且病程<5年，第二组为糖尿病病程5 - 10年，第三组为糖尿病病程超过10年。测量血脂水平、hs-CRP水平和ACR。
结果
第一组中hs CRP与ACR及甘油三酯之间存在相关性，第一组中hs CRP与ACR及甘油三酯之间存在相关性。在第二组中，hs CRP与ACR显示出显著相关性，而在第三组中，观察到与ACR、低密度脂蛋白（LDL）和胆固醇存在显著相关性。
结论
发现糖尿病病程较长的患者hs CRP和ACR水平较高。
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