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新型冠状病毒肺炎信使核糖核酸疫苗接种与镓[68Ga]奥曲肽正电子发射断层扫描/计算机断层扫描显示腋窝放射性药物摄取异常

COVID-19 messenger ribonucleic acid vaccination and abnormal radiopharmaceutical uptake in the axilla visualized on Ga-DOTATATE positron-emission tomography/computed tomography.

作者信息

Weissman Joshua Philip, Bartel Twyla

机构信息

Department of Radiology, Northwestern University Feinberg, School of Medicine, Northwestern University Feinberg, Chicago, IL, USA.

Department of Radiology, Global Advanced Imaging, PLLC, Little Rock, Arkansas, USA.

出版信息

World J Nucl Med. 2021 Aug 20;20(4):392-394. doi: 10.4103/wjnm.wjnm_54_21. eCollection 2021 Oct-Dec.

Abstract

As COVID-19 vaccination rates continue to rise, it is becoming increasingly important to understand diagnostic imaging associations' resultant from the vaccines. Here, we report a case of a 59-year-old female who was in remission for gastrointestinal neuroendocrine carcinoma and presented for standard follow-up imaging evaluation. Positron-emission tomography (PET) images from a Ga-DOTATATE PET (NETSPOT) demonstrated moderate focal radiotracer uptake in the right axilla. Interestingly, this uptake localized to several normal-sized lymph nodes on the corresponding computed tomography (CT). A medical history revealed the patient received both doses of an ipsilateral COVID-19 messenger ribonucleic acid vaccine injection at 17 and 38 days before the PET/CT study. Subsequent scans 2 months later revealed no radiotracer uptake.

摘要

随着新冠病毒疫苗接种率持续上升,了解疫苗导致的诊断性影像关联变得越发重要。在此,我们报告一例59岁女性病例,该患者的胃肠道神经内分泌癌处于缓解期,前来进行标准的随访影像评估。来自镓[68Ga] DOTATATE正电子发射断层显像(PET)(NETSPOT)的图像显示右腋窝有中度局灶性放射性示踪剂摄取。有趣的是,这种摄取位于相应计算机断层扫描(CT)上的几个大小正常的淋巴结处。病史显示,该患者在PET/CT检查前17天和38天接受了同侧的两剂新冠病毒信使核糖核酸疫苗注射。2个月后的后续扫描显示无放射性示踪剂摄取。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b6dd/8686744/bb4761b35b25/WJNM-20-392-g001.jpg

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