Mariita Richard M, Peterson James W
Crystal IS Inc., an Asahi Kasei company, Green Island, New York, 12183, USA.
Access Microbiol. 2021 Nov 2;3(11):000276. doi: 10.1099/acmi.0.000276. eCollection 2021.
SARS-CoV-2 is mostly transmitted through close contact with infected people by infected aerosols and fomites. Ultraviolet subtype C (UVC) lamps and light-emitting diodes can be used to disrupt the transmission chain by disinfecting fomites, thus managing the disease outbreak progression. Here, we assess the ultraviolet wavelengths that are most effective in inactivation of SARS-CoV-2 on fomites. Variations in UVC wavelengths impact the dose required for disinfection of SARS-CoV-2 and alter how rapidly and effectively disruption of the virus transmission chain can be achieved. This study reveals that shorter wavelengths (254-268 nm) take a maximum of 6.25 mJ/cm over 5 s to obtain a target SARS-CoV-2 reduction of 99.9%. Longer wavelengths, like 280 nm, take longer irradiation time and higher dose to inactivate SARS-CoV-2. These observations emphasize that SARS-CoV-2 inactivation is wavelength-dependent.
严重急性呼吸综合征冠状病毒2（SARS-CoV-2）主要通过与感染者密切接触，经由受感染的气溶胶和污染物传播。C型紫外线（UVC）灯和发光二极管可用于对污染物进行消毒，从而切断传播链，进而控制疾病暴发的进程。在此，我们评估了对污染物上的SARS-CoV-2灭活最有效的紫外线波长。UVC波长的变化会影响SARS-CoV-2消毒所需的剂量，并改变实现病毒传播链中断的速度和效果。本研究表明，较短波长（254-268纳米）在5秒内最多需要6.25毫焦/平方厘米，才能使目标SARS-CoV-2减少99.9%。较长波长，如280纳米，则需要更长的照射时间和更高的剂量才能灭活SARS-CoV-2。这些观察结果强调，SARS-CoV-2的灭活取决于波长。
