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对患有神经发育障碍的青少年和青年的日常生活社交互动进行特征描述:自闭症谱系障碍患者与22q11.2缺失综合征患者的比较。

Characterizing Daily-Life Social Interactions in Adolescents and Young Adults with Neurodevelopmental Disorders: A Comparison Between Individuals with Autism Spectrum Disorders and 22q11.2 Deletion Syndrome.

作者信息

Feller Clémence, Ilen Laura, Eliez Stephan, Schneider Maude

机构信息

Clinical Psychology Unit for Intellectual and Developmental Disabilities, Faculty of Psychology and Educational Sciences, University of Geneva, 40, Boulevard du Pont-d'Arve, 1205, Geneva, Switzerland.

Developmental Imaging and Psychopathology Lab Research Unit, Faculty of Medicine, University of Geneva, Geneva, Switzerland.

出版信息

J Autism Dev Disord. 2023 Jan;53(1):245-262. doi: 10.1007/s10803-021-05423-9. Epub 2022 Jan 11.

Abstract

Social impairments are common features of 22q11.2 deletion syndrome (22q11DS) and autism spectrum disorders (ASD). The Ecological Momentary Assessment (EMA) allowed access to daily-life information in order to explore the phenomenology of social interactions. 32 individuals with 22q11DS, 26 individuals with ASD and 44 typically developing peers (TD) aged 12-30 were assessed during 6 days 8 times a day using a mobile app. Participants with 22q11DS and ASD did not spend more time alone but showed distinct implication in the social sphere than TD. Distinct profiles emerged between the two conditions regarding the subjective experience of aloneness and the subjective experience of social interactions. This study highlights distinct social functioning profiles in daily-life in 22q11DS and ASD that points towards different therapeutic targets.

摘要

社交障碍是22q11.2缺失综合征(22q11DS)和自闭症谱系障碍(ASD)的常见特征。生态瞬时评估(EMA)能够获取日常生活信息,以探究社交互动的现象学。使用一款移动应用程序,对32名患有22q11DS的个体、26名患有ASD的个体以及44名年龄在12至30岁之间的典型发育同龄人(TD)进行了为期6天、每天8次的评估。患有22q11DS和ASD的参与者独处时间并未增加,但在社交领域的参与程度与TD不同。在孤独的主观体验和社交互动的主观体验方面,两种情况呈现出不同的特征。这项研究突出了22q11DS和ASD在日常生活中不同的社交功能特征,这指向了不同的治疗靶点。

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