Bucks Breast Unit, Buckinghamshire Healthcare NHS Trust, High Wycombe, HP11 2TT, UK.
Future Oncol. 2022 Feb;18(4):437-443. doi: 10.2217/fon-2021-0970. Epub 2022 Jan 12.
This study aimed to explore the hypothesis that the stage of breast cancer at initial diagnosis in 2020 is more advanced compared with 2019. Tumor, node, metastasis and Union for International Cancer Control (UICC) stages of new breast cancer diagnoses at the Bucks Breast Unit from May 2019 to October 2020 were reviewed. A p < 0.05 was considered significant. Average UICC stage increased from 1a in 2019 to 2a in 2020 (p < 0.01). Excluding cancers detected through screening, UICC stage still increased from 1b in 2019 to 2a in 2020 (p = 0.0184). There was a significant increase in the percentage of node-positive patients (p = 0.0063) and patients with metastatic disease (p = 0.0295) on initial presentation. Overall, patients presented with higher UICC stages and more node-positive and metastatic disease on initial diagnosis in 2020 compared with 2019.
本研究旨在探讨 2020 年初诊乳腺癌分期较 2019 年更为晚期的假设。回顾了 2019 年 5 月至 2020 年 10 月 Bucks 乳腺科新诊断乳腺癌的肿瘤、淋巴结、转移和国际抗癌联盟（UICC）分期。p<0.05 被认为具有统计学意义。平均 UICC 分期从 2019 年的 1a 期增加到 2020 年的 2a 期（p<0.01）。排除通过筛查发现的癌症后，UICC 分期仍从 2019 年的 1b 期增加到 2020 年的 2a 期（p=0.0184）。初诊时淋巴结阳性患者（p=0.0063）和转移性疾病患者（p=0.0295）的百分比显著增加。总体而言，与 2019 年相比，2020 年患者的 UICC 分期更高，淋巴结阳性和转移性疾病更多。
