Clin Lab. 2022 Jan 1;68(1). doi: 10.7754/Clin.Lab.2021.210429.
According to the latest data, the detection rate of echinococcus in Hoboksar Mongol Autonomous County was 3.7%. The objective of this study is to further investigate the epidemiology of echinococcosis in Ho-boksar Mongol Autonomous County of Xinjiang Uygur Autonomous Region, People's Republic of China and provide the scientific evidence for preventive and control measures.
We performed ultrasound examination of 521 people in Hoboksar Mongol Autonomous County of Xinjiang Autonomous Region, and collected 508 serum samples, which were analyzed with enzyme-linked immunosorbent assay. Data were analyzed by t-test and multinomial logistic regression for risk factor analysis. We collected 126 pieces of herder's dog feces and used double antibody sandwich method to detect the positive rate of fecal antigen.
The prevalence rate of human echinococcosis in this region was 4.4% (23/521), including 4.0% (21/521) for cystic echinococcosis (CE), 0.38% (2/521) for alveolar echinococcosis (AE). It was found that CE seropositivity was significantly different from gender, age, ethnic group, occupation, culture, area, income and awareness of this disease. The seroprevalence rate of people aged 41 - 65 (3.74%) was higher than of age 0 - 17 (0.197%) (p > 0.05); Female serological positive (4.921%) was higher than male (1.772%) (p > 0.005); Mongolian serological positive (5%) was higher than Han (0.197%) and Kazakhs (1.181%) (p > 0.05); The herdsmen serological positive (2.756% was higher than students (0.197%) (p > 0.05); The primary school students serological positive (2.559%) was higher than children before school 0% (p > 0.05); Chagankule serological positive (9.211%) was higher than Bayinaow (8.497%) (p > 0.05); The seroprevalence rate of people with income < 2,000 (3.74%) was higher than people with income over 5,000 (0.197%) (p > 0.05); The seroprevalence rate of people who had no disease awareness (4.724%) was higher than those who had awareness of Hydatid disease (1.969%) (p < 0.05). Multivariate logistic regression show age, ethic group and awareness of station are the influence factors of epidemiology of echinococcosis. Canine fecal antigen positive rate was 50% (p > 0.05). Narenhebuke (48.78%) was higher than chahet (20.00%), but there is no statistical difference (p > 0.05).
The surveillance data and our study results tend to be consistent that echinococcosis has an increasing trend in Hoboksar Mongol Autonomous County. Efforts should be continued, in both animals and humans by increasing training campaigns and public awareness.
根据最新数据，霍城县蒙古自治县的包虫病检出率为 3.7%。本研究的目的是进一步调查中国新疆维吾尔自治区霍城县的包虫病流行病学情况，为预防和控制措施提供科学依据。
对新疆霍城县 521 人进行超声检查，并采集 508 份血清样本，采用酶联免疫吸附试验进行分析。采用 t 检验和多因素逻辑回归进行危险因素分析。我们收集了 126 份牧民狗的粪便，并用双抗体夹心法检测粪便抗原的阳性率。
该地区人群包虫病患病率为 4.4%（23/521），其中囊性包虫病（CE）为 4.0%（21/521），泡型包虫病（AE）为 0.38%（2/521）。结果表明，CE 血清阳性率与性别、年龄、民族、职业、文化、地区、收入和对该病的认识有关。41-65 岁人群的血清阳性率（3.74%）高于 0-17 岁人群（0.197%）（p>0.05）；女性血清阳性率（4.921%）高于男性（1.772%）（p>0.005）；蒙古族血清阳性率（5%）高于汉族（0.197%）和哈萨克族（1.181%）（p>0.05）；牧民血清阳性率（2.756%）高于学生（0.197%）（p>0.05）；小学生血清阳性率（2.559%）高于学龄前儿童（0%）（p>0.05）；查干库勒血清阳性率（9.211%）高于巴音那木（8.497%）（p>0.05）；收入<2000 元人群的血清阳性率（3.74%）高于收入>5000 元人群（0.197%）（p>0.05）；无疾病知晓率人群的血清阳性率（4.724%）高于有疾病知晓率人群（1.969%）（p<0.05）。多因素逻辑回归显示，年龄、民族和疾病知晓是包虫病流行病学的影响因素。犬粪抗原阳性率为 50%（p>0.05）。那仁河布克（48.78%）高于查特（20.00%），但无统计学差异（p>0.05）。
监测数据和我们的研究结果表明，霍城县的包虫病呈上升趋势。应继续努力，通过加强培训和提高公众意识，在人和动物中开展工作。
