Department of Biochemistry All India Institute of Medical Sciences, Bhopal, Madhya Pradesh-462020, India.
Independent Researcher, Bhopal, Madhya Pradesh, India.
Infect Disord Drug Targets. 2022;22(4):e170122200309. doi: 10.2174/1871526522666220117153838.
Herd immunity can only be achieved when it is extended to the population level. When a sufficiently significant fraction of immune individuals exists in a group, it confers indirect protection from infection to vulnerable individuals. This population-level effect is frequently considered in the context of vaccination programs, which attempt to build herd immunity so that people who cannot be vaccinated, such as the very young or those with impaired immune systems, are nonetheless protected from disease. Clinical signs are at times poor predictor of transmissibility for some infections, such as COVID-19, because asymptomatic hosts can be extremely infectious and contribute to the spread of the virus. COVID-19 is a quickly evolving issue that has been widely spread throughout the world. This article elaborates the idea and goal of herd immunity, the necessary conditions for realizing herd immunity, the restrictive requirements for applying herd immunity, and the obstacles experienced in achieving herd immunity in the context of COVID-19. This mini-article explains the concept and purpose of herd immunization in the context of COVID-19.
群体免疫只有在扩展到人群层面时才能实现。当一个群体中存在足够多的免疫个体时,它会为易感染人群提供间接的感染保护。这种群体层面的效应在疫苗接种计划中经常被考虑,这些计划试图建立群体免疫,以使那些不能接种疫苗的人,如非常年幼或免疫系统受损的人,仍然能够免受疾病的侵害。对于某些传染病,如 COVID-19,临床症状有时并不能很好地预测其传染性,因为无症状宿主可能具有极强的传染性,并导致病毒的传播。COVID-19 是一个迅速演变的问题,已经在全球范围内广泛传播。本文阐述了群体免疫的概念和目标、实现群体免疫的必要条件、应用群体免疫的限制要求,以及在 COVID-19 背景下实现群体免疫所面临的障碍。这篇小文章解释了 COVID-19 背景下群体免疫的概念和目的。