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如何理解 COVID-19 大流行中的群体免疫。

How to Understand Herd Immunity in the Context of COVID-19.

机构信息

The Second Clinical School Affiliated Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Department of Thoracic Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

出版信息

Viral Immunol. 2021 Apr;34(3):174-181. doi: 10.1089/vim.2020.0195. Epub 2020 Dec 21.

Abstract

COVID-19 is an emerging rapidly evolving situation, which is widely disseminated all over the world. During this period, the concept of herd immunity is often mentioned, but it is easily misunderstood. In the context of COVID-19, this article comprehensively expounds the concept and purpose of herd immunity, the necessary conditions for realizing the herd immunity, the restrictive conditions for the application of herd immunity, and the challenges faced by the realization of herd immunity. Furthermore, starting from the "three elements," which refers to the characteristics of the pathogen and the population, as well as the behaviors taken by the population, the relationship between herd immunity and COVID-19 is deeply analyzed. Based on the aforementioned, the implementation of corresponding measures is expected to slow down the spread of the epidemic and even eliminate pathogens.

摘要

COVID-19 是一种迅速发展的新兴情况,在全球范围内广泛传播。在此期间,经常提到群体免疫的概念,但它很容易被误解。在 COVID-19 的背景下,本文全面阐述了群体免疫的概念和目的、实现群体免疫的必要条件、群体免疫应用的限制条件,以及实现群体免疫所面临的挑战。此外,本文还从病原体和人群的特征以及人群采取的行为这“三个要素”出发,深入分析了群体免疫与 COVID-19 之间的关系。基于上述内容,期望实施相应的措施来减缓疫情的传播,甚至消灭病原体。

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